Evidence map›Paper›PMID 24489841›Full record

Trial reportPloS one2014

NIMH Project Accept (HPTN 043): results from in-depth interviews with a longitudinal cohort of community members.

Suzanne Maman, Heidi van Rooyen, Petra Stankard, Alfred Chingono, Tshifhiwa Muravha, Jacob Ntogwisangu, Zipho Phakathi, Namtip Srirak, Stephen F Morin, NIMH Project Accept (HPTN 043) study team

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 5 countries.

Suzanne MamanDepartment of Health Behavior, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Heidi van RooyenSocial, Behavioural and Biomedical Interventions Unit, Human Sciences Research Council, Pieternaritzburg, South Africa.
Petra StankardDepartment of Health Behavior, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Alfred ChingonoDepartment of Psychiatry, University of Zimbabwe. Harare, Zimbabwe.
Tshifhiwa MuravhaPerinatal HIV Research Unit, Witswatersrand University, Soweto, South Africa.
Jacob NtogwisanguDepartment of Psychiatry and Mental Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Zipho PhakathiSocial, Behavioural and Biomedical Interventions Unit, Human Sciences Research Council, Pieternaritzburg, South Africa.
Namtip SrirakResearch Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.
Stephen F MorinCenter for AIDS Prevention Studies, University of California San Francisco, San Francisco, Califorinia, United States of America.
NIMH Project Accept (HPTN 043) study team
Human Sciences Research Council · ZAUniversity of North Carolina at Chapel Hill · USChiang Mai University · THMuhimbili University of Health and Allied Sciences · TZPerinatal HIV Research Unit · ZAUniversity of California, San Francisco · USUniversity of Zimbabwe · ZW

Funding

Leadership for HIV/AIDS Clinical Trials Networks; HIV Prevention Trials NetworkU01AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI DONNELL, DEBORAH J · 2006 to 2010
$28.8M
Community-Based HIV VCT: South AfricaU01MH066701 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI COATES, THOMAS J. · 2003 to 2010
$24.3M
HIV Prevention Trials Network: Network LaboratoryU01AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI ESHLEMAN, SUSAN H · 2006 to 2010
$16.5M
International Studies of the Acquired Immune Deficiency Syndrome (AIDS)ZIAAI000361 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI REDD, ANDREW · 2009 to 2025
$15.8M
Community-Based VCT: ZimbabweU01MH066702 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MORIN, STEPHEN F · 2003 to 2010
$13.4M
Community-Based VCT: TanzaniaU01MH066688 · NIMH · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SWEAT, MICHAEL D · 2003 to 2010
$11.7M
Community-Based VCT: ThailandU01MH066687 · NIMH · JOHNS HOPKINS UNIVERSITY · PI CELENTANO, DAVID D. · 2003 to 2010
$9.8M
NIAID NIH HHS U01 AI068613NIAID NIH HHS U01AI068613NIAID NIH HHS U01 AI068617NIAID NIH HHS U01AI068617NIMH NIH HHS U01 MH066687NIMH NIH HHS U01MH066687NIMH NIH HHS U01 MH066688NIMH NIH HHS U01MH066688NIMH NIH HHS U01 MH066701NIMH NIH HHS U01MH066701NIMH NIH HHS U01 MH066702NIMH NIH HHS U01MH066702PHS HHS UM1A068619Wellcome Trust 097410
6 · The paper itself

Abstract

introductionNIMH Project Accept (HPTN 043) is a community- randomized trial to test the safety and efficacy of a community-level intervention designed to increase testing and lower HIV incidence in Tanzania, Zimbabwe, South Africa and Thailand. The evaluation design included a longitudinal study with community members to assess attitudinal and behavioral changes in study outcomes including HIV testing norms, HIV-related discussions, and HIV-related stigma.

methodsA cohort of 657 individuals across all sites was selected to participate in a qualitative study that involved 4 interviews during the study period. Baseline and 30-month data were summarized according to each outcome, and a qualitative assessment of changes was made at the community level over time.

resultsMembers from intervention communities described fewer barriers and greater motivation for testing than those from comparison communities. HIV-related discussions in intervention communities were more grounded in personal testing experiences. A change in HIV-related stigma over time was most pronounced in Tanzania and Zimbabwe. Participants in the intervention communities from these two sites attributed community-level changes in attitudes to project specific activities. DISCUSSION: The Project Accept intervention was associated with more favorable social norms regarding HIV testing, more personal content in HIV discussions in all study sites, and qualitative changes in HIV-related stigma in two of five sites.

Indexed as

Health Knowledge, Attitudes, PracticeAdolescentAdultAfricaCommunity ParticipationFemaleHIV InfectionsHumansInterviews as TopicLongitudinal StudiesMaleQualitative ResearchSocial StigmaThailand

Identifiers

PMID24489841
PMCPMC3906114
OpenAlexW2090166976

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.