ArticlePloS one2014
QTL dissection of Lag phase in wine fermentation reveals a new translocation responsible for Saccharomyces cerevisiae adaptation to sulfite.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed, 113 citations in OpenAlex.
- From Oak to Wine: Evolution, Admixture, and Adaptation of California and British Columbia Saccharomyces Cerevisiae Wine Strains.Genome biology and evolution · 2026Article
- Genetic suppressor of autophagy defects in huntingtin null cells identified using a mutagenesis screen in Dictyostelium discoideum.BMC molecular and cell biology · 2026Article
- Distribution of yeast species and their resistance to copper and sulfite across arboreal and viticulture habitats.FEMS yeast research · 2026Article
- Genomic tales of wine yeasts: from domestication to functional innovation.FEMS yeast research · 2026Review
- From one genome to thousands, and beyond.FEMS yeast research · 2026Review
- Genomic adaptation of an autochthonous cider yeast strain to buckwheat and barley wort under stressful brewing conditions.Applied and environmental microbiology · 2025Article
- Biocontainment efficacy redefined.Applied and environmental microbiology · 2025Article
- Colonization of vineyards by non-bioRxiv : the preprint server for biology · 2025Article
- Enhancing recombinant protein production through Cre-loxP mediated chromosomal rearrangement evolution in Kluyveromyces marxianus.Communications biology · 2025Article
- Wine Fermentation as a Model System for Microbial Ecology and Evolution.Environmental microbiology · 2025Review
- Identification of quantitative trait loci (QTLs) for key cheese making phenotypes in the blue-cheese mold Penicillium roqueforti.PLoS genetics · 2025Article
- ScRAPdb: an integrated pan-omics database for the Saccharomyces cerevisiae reference assembly panel.Nucleic acids research · 2025Article
- Article
- The distribution of beneficial mutational effects between two sister yeast species poorly explains natural outcomes of vineyard adaptation.bioRxiv : the preprint server for biology · 2024Article
- Copper-based grape pest management has impacted wine aroma.Scientific reports · 2024Article
- Domestication signatures in the non-conventional yeastmSystems · 2024Article
- SO2 and copper tolerance exhibit an evolutionary trade-off in Saccharomyces cerevisiae.PLoS genetics · 2023Article
- Endo metabolomic profiling ofFrontiers in microbiology · 2023Article
- Genomic Adaptations ofMicroorganisms · 2022Review
- Truth in wine yeast.Microbial biotechnology · 2022Review
1 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quantitative genetics and QTL mapping are efficient strategies for deciphering the genetic polymorphisms that explain the phenotypic differences of individuals within the same species. Since a decade, this approach has been applied to eukaryotic microbes such as Saccharomyces cerevisiae in order to find natural genetic variations conferring adaptation of individuals to their environment. In this work, a QTL responsible for lag phase duration in the alcoholic fermentation of grape juice was dissected by reciprocal hemizygosity analysis. After invalidating the effect of some candidate genes, a chromosomal translocation affecting the lag phase was brought to light using de novo assembly of parental genomes. This newly described translocation (XV-t-XVI) involves the promoter region of ADH1 and the gene SSU1 and confers an increased expression of the sulfite pump during the first hours of alcoholic fermentation. This translocation constitutes another adaptation route of wine yeast to sulfites in addition to the translocation VIII-t-XVI previously described. A population survey of both translocation forms in a panel of domesticated yeast strains suggests that the translocation XV-t-XVI has been empirically selected by human activity.
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