ArticleInternational journal of endocrinology2013
Prognosis of multifocal papillary thyroid carcinoma.
Article in International journal of endocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Risk Factors for Contralateral Occult Carcinoma in Patients With Unilateral Papillary Thyroid Carcinoma: A Retrospective Study and Meta-Analysis.Frontiers in endocrinology · 2021Pooled it
- Impact of Tumor Bilaterality and Multifocality in Predicting Recurrence of Papillary Thyroid Carcinoma: A Retrospective Cohort Study.Endocrinology and metabolism (Seoul, Korea) · 2026Article
- Clinical Impact of Multifocality and Bilaterality on Lymph Node Metastasis in Papillary Thyroid Microcarcinoma.Diagnostics (Basel, Switzerland) · 2026Article
- Multifocal papillary thyroid microcarcinomas: is the total tumor diameter associated with the tumor behavior? A retrospective cohort study.Einstein (Sao Paulo, Brazil) · 2025Article
- Minimally Invasive Thermal Ablation for Papillary Thyroid Microcarcinoma: Feasibility Analysis in Primary Healthcare Settings.International journal of endocrinology · 2025Review
- The differences between unilateral multifocality and bilateral multifocality in papillary thyroid carcinoma: a retrospective cohort study.Gland surgery · 2024Article
- The Impact of Total Tumor Diameter on Lymph Node Metastasis and Tumor Recurrence in Papillary Thyroid Carcinomas.Diagnostics (Basel, Switzerland) · 2024Article
- Multifocal papillary thyroid cancer in Graves' disease: A case report.World journal of clinical cases · 2023Article
- Association between papillary thyroid carcinoma and lymphocytic thyroiditis: A retrospective study.Oncology letters · 2023Article
- Preoperative risk stratification for patients with ≤ 1 cm papillary thyroid carcinomas based on preoperative blood inflammatory markers: construction of a dynamic predictive model.Frontiers in endocrinology · 2023Article
- Validation of Ultrasound Risk Stratification Systems for Cervical Lymph Node Metastasis in Patients with Thyroid Cancer.Cancers · 2022Article
- Article
- Outcomes of nonsuspicious contralateral nodules with active surveillance after lobectomy in patients with papillary thyroid carcinoma.Frontiers in endocrinology · 2022Article
- Risk factor score for the prediction of central compartment lymph node metastasis in papillary thyroid carcinoma and its clinical significance.Frontiers in surgery · 2022Article
- Hemithyroidectomy for Thyroid Cancer: A Review.Medicina (Kaunas, Lithuania) · 2020Review
- Predictive factors of lateral lymph node metastasis in conventional papillary thyroid carcinoma.Gland surgery · 2020Article
- Total tumor diameter: the neglected value in papillary thyroid microcarcinoma.Journal of endocrinological investigation · 2020Article
- [Current controversies in risk-adapted therapy in differentiated thyroid cancer: Is less (therapy) really more?]Wiener medizinische Wochenschrift (1946) · 2020Article
- Management of Clinically Solitary Papillary Thyroid Carcinoma Patients According to Risk-Scoring Model for Contralateral Occult Carcinoma.Frontiers in endocrinology · 2020Article
- Should multifocality be an indication for completion thyroidectomy in papillary thyroid carcinoma?Surgery · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study was to investigate the clinical features and therapeutic outcomes of multifocal papillary thyroid microcarcinoma (PTMC). A total of 2,418 papillary thyroid carcinoma (PTC) patients had undergone thyroidectomy in one medical center between 1977 and 2010. There were 483 (20.0%) diagnosed with multifocal PTC. The percentage of multifocal PTC was higher in PTMC patients (22.0%) than in non-PTMC patients (19.5%). Demographic and clinical characteristics of PTMC and multifocal PTC in PTC patients were traced. Multifocal PTC patients presented with smaller tumors at an older age, and a higher percentage underwent total or complete thyroidectomy. These patients also showed a higher incidence of postoperative disease progression than did unifocal PTC patients. Comparison of 483 patients with multifocal PTMC and non-PTMC tumors showed a higher incidence of postoperative disease progression in patients with non-PTMC; otherwise, there was no statistical difference in disease-specific and total mortality between these two groups. In conclusion, the incidence of multifocal PTMC was not lower than that of non-PTMC, and postoperative therapies were necessary for both multifocal PTMC and non-PTMC patients.
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Registered trials
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