Evidence map›Paper›PMID 24489507›Full record

SynthesisTheScientificWorldJournal2013

Pancreaticobiliary maljunction is associated with common bile duct carcinoma: a meta-analysis.

Yang Li, Jun Wei, Zhongxin Zhao, Tiangeng You, Mingan Zhong

Abstract readMeta-Analysis
In one paragraph

Synthesis in TheScientificWorldJournal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Pancreaticobiliary maljunction and biliary cancer.Journal of gastroenterology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yang LiDepartment of Gastrointestinal Surgery, East Hospital, Tongji University, 150 Jimo Road, Pudong New District, Shanghai 200120, China.
Jun WeiDepartment of Gastrointestinal Surgery, East Hospital, Tongji University, 150 Jimo Road, Pudong New District, Shanghai 200120, China.
Zhongxin ZhaoDepartment of Gastrointestinal Surgery, East Hospital, Tongji University, 150 Jimo Road, Pudong New District, Shanghai 200120, China.
Tiangeng YouDepartment of Gastrointestinal Surgery, East Hospital, Tongji University, 150 Jimo Road, Pudong New District, Shanghai 200120, China.
Mingan ZhongDepartment of Gastrointestinal Surgery, East Hospital, Tongji University, 150 Jimo Road, Pudong New District, Shanghai 200120, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePancreaticobiliary maljunction (PBM) has been reported to be associated with an increased risk of gallbladder carcinoma. However, the relationship between PBM and common bile duct carcinoma (CBDC) remains unclear. We aimed to conduct a meta-analysis to determine the available evidence on the association between PBM and CBDC.

methodsThe pooled odds ratio (OR) and standard mean differences (SMD) with 95% confidence interval (95% CI) were used to estimate the effects.

resultsA total of eight case-control studies and two cohort studies were identified. The incidence of PBM was higher in CBDC patients than in controls (OR = 1.45; 95% CI, 1.19-1.76). Compared with patients without PBM, CBDC patients with PBM were younger at the diagnosis age (SMD = -0.46; 95% CI, -0.64 to -0.28). A difference in the incidence of associated CDC was found between CBDC patients with or without PBM (OR = 2.14; 95% CI, 1.60-2.87).

conclusionsCompared with benign biliary tract diseases, the incidence of PBM was higher in CBDC patients, especially in relatively young patients. We also found that the incidence of CDC was higher in CBDC patients with PBM. These findings showed positive association between PBM and CBDC, which may help in identifying high-risk individuals.

Indexed as

Age of OnsetBile Duct NeoplasmsBile DuctsCommon Bile DuctHumansIncidenceOdds RatioPancreatic DuctsPublication Bias

Identifiers

PMID24489507
PMCPMC3893009

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.