Evidence map›Paper›PMID 24489486›Full record

ArticleSIAM journal on applied dynamical systems2013

Locally Contractive Dynamics in Generalized Integrate-and-Fire Neurons.

Nicolas D Jimenez, Stefan Mihalas, Richard Brown, Ernst Niebur, Jonathan Rubin

Abstract read
In one paragraph

Article in SIAM journal on applied dynamical systems, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Synchronization of Electrically Coupled Resonate-and-Fire Neurons.SIAM journal on applied dynamical systems · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicolas D JimenezAllen Institute for Brain Science, Seattle, WA 98103.
Stefan MihalasAllen Institute for Brain Science, Seattle, WA 98103.
Richard BrownDepartment of Mathematics, Johns Hopkins University, Baltimore, MD 21218.
Ernst NieburDepartment of Neuroscience, Johns Hopkins University, Baltimore, MD 21205.
Jonathan RubinDepartment of Mathematics, University of Pittsburgh, Pittsburgh, PA 15260.

Funding

CRCNS-Attentional Selection and Perceptual OrganizationR01EY016281 · NEI · JOHNS HOPKINS UNIVERSITY · PI NIEBUR, ERNST · 2004 to 2012
$2.9M
NEI NIH HHS R01 EY016281
6 · The paper itself

Abstract

Integrate-and-fire models of biological neurons combine differential equations with discrete spike events. In the simplest case, the reset of the neuronal voltage to its resting value is the only spike event. The response of such a model to constant input injection is limited to tonic spiking. We here study a generalized model in which two simple spike-induced currents are added. We show that this neuron exhibits not only tonic spiking at various frequencies but also the commonly observed neuronal bursting. Using analytical and numerical approaches, we show that this model can be reduced to a one-dimensional map of the adaptation variable and that this map is locally contractive over a broad set of parameter values. We derive a sufficient analytical condition on the parameters for the map to be globally contractive, in which case all orbits tend to a tonic spiking state determined by the fixed point of the return map. We then show that bursting is caused by a discontinuity in the return map, in which case the map is

Indexed as

burstingcontraction analysishybrid dynamical systemsintegrate-and-fireMihalas–Niebur neuronpiecewise contractions

Identifiers

PMID24489486
PMCPMC3902217

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.