ArticleChemistry of materials : a publication of the American Chemical Society2013
Thermoresponsive composite hydrogels with aligned macroporous structure by ice-templated assembly.
Article in Chemistry of materials : a publication of the American Chemical Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Freeze-Derived Microporous Biomaterials for Tissue Engineering Applications.Smart medicine · 2026Review
- Highly oriented hydrogels for tissue regeneration: design strategies, cellular mechanisms, and biomedical applications.Theranostics · 2024Review
- Macroporous Granular Hydrogels Functionalized with Aligned Architecture and Small Extracellular Vesicles Stimulate Osteoporotic Tendon-To-Bone Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Programmable nanocomposites of cellulose nanocrystals and zwitterionic hydrogels for soft robotics.Nature communications · 2023Article
- Anisotropic Bi-Layer Hydrogel Actuator with pH-Responsive Color-Changing and Photothermal-Responsive Shape-Changing Bi-Functional Synergy.Gels (Basel, Switzerland) · 2023Article
- Architected Metal Selenides via Sequential Cation and Anion Exchange on Self-Organizing Nanocomposites.Chemistry of materials : a publication of the American Chemical Society · 2023Article
- In situ determination of the extreme damage resistance behavior in stomatopod dactyl club.Journal of synchrotron radiation · 2022Article
- Patterned vascularization in a directional ice-templated scaffold of decellularized matrix.Engineering in life sciences · 2021Article
- Electrothermal soft manipulator enabling safe transport and handling of thin cell/tissue sheets and bioelectronic devices.Science advances · 2020Article
- Anisotropic, porous hydrogels templated by lyotropic chromonic liquid crystals.Journal of materials chemistry. B · 2020Article
- Cryopolymerization enables anisotropic polyaniline hybrid hydrogels with superelasticity and highly deformation-tolerant electrochemical energy storage.Nature communications · 2020Article
- Tripolyphosphate-Crosslinked Chitosan/Gelatin Biocomposite Ink for 3D Printing of Uniaxial Scaffolds.Frontiers in bioengineering and biotechnology · 2020Article
- A Facile Method to Fabricate Anisotropic Extracellular Matrix with 3D Printing Topological Microfibers.Materials (Basel, Switzerland) · 2019Article
- Composite bijel-templated hydrogels for cell delivery.ACS biomaterials science & engineering · 2018Article
- Yeast fermentation inspired Ca-alginate hydrogel membrane: lower transparency, hierarchical pore structure and higher hydrophobicity.RSC advances · 2018Article
- Aragonite-Associated Mollusk Shell Protein Aggregates To Form Mesoscale "Smart" Hydrogels.ACS omega · 2016Article
- Interfacial undercooling in solidification of colloidal suspensions: analyses with quantitative measurements.Scientific reports · 2016Article
- Hydrogels as a Replacement Material for Damaged Articular Hyaline Cartilage.Materials (Basel, Switzerland) · 2016Review
- Biomimetic gradient scaffold from ice-templating for self-seeding of cells with capillary effect.Acta biomaterialia · 2015Article
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Authors and funding
4 authors.
Funding
Abstract
Natural tissues, such as bone, tendon, and muscle, have well defined hierarchical structures, which are crucial for their biological and mechanical functions. However, mimicking these structural features still remains a great challenge. In this study, we use ice-templated assembly and UV-initiated cryo-polymerization to fabricate a novel kind of composite hydrogel which have both aligned macroporous structure at micrometer scale and a nacre-like layered structure at nanoscale. Such hydrogels are macroporous, thermoresponsive, and exhibit excellent mechanical performance (tough and high stretchable), attractive properties that are of significant impact on the wide applications of composite hydrogels, especially as tissue-engineering scaffolds. The fabrication method in this study including freeze-casting and cryo-polymerization can also be applied to other materials, which makes it promising for designing and developing smart and multifunctional composite hydrogels with hierar chical structures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.