ArticleAnnals of botany2014
GPT2: a glucose 6-phosphate/phosphate translocator with a novel role in the regulation of sugar signalling during seedling development.
Article in Annals of botany, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24 citing papers in PubMed, 33 citations in OpenAlex.
- Genetic Dynamics of Allotetraploid Cotton Species (Plants (Basel, Switzerland) · 2026Article
- ARABIDOPSIS Bsister and SEEDSTICK MADS-box transcription factors modulate maternal nutrient flow for seed development in Arabidopsis.Nature communications · 2026Article
- Comprehensive DIA-MS Proteomics of Root Basal Nodes Elucidates Mechanisms of Salt Tolerance in Rice.Proteomics · 2026Article
- A Role for the Plastidial GPT2 Translocator in the Modulation of Lignin Biosynthesis.Plant, cell & environment · 2025Article
- Genome-wide association analysis and linkage mapping decipher the genetic control of primary metabolites and quality traits in Capsicum.The Plant journal : for cell and molecular biology · 2025Article
- Photosynthetic acclimation to changing environments.Biochemical Society transactions · 2023Review
- Glucose-6-P/phosphate translocator2 mediates the phosphoglucose-isomerase1-independent response to microbial volatiles.Plant physiology · 2022Article
- Recruitment of an ancient branching program to suppress carpel development in maize flowers.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Expression of a plastid-localized sugar transporter in the suspensor is critical to embryogenesis.Plant physiology · 2021Article
- Acclimation of Photosynthesis to Changes in the Environment Results in Decreases of Oxidative Stress inFrontiers in plant science · 2021Article
- The Arabidopsis Plastidial Glucose-6-Phosphate Transporter GPT1 is Dually Targeted to Peroxisomes via the Endoplasmic Reticulum.The Plant cell · 2020Article
- Transcriptome analysis of potato shoots, roots and stolons under nitrogen stress.Scientific reports · 2020Article
- WRKY18 and WRKY53 Coordinate with HISTONE ACETYLTRANSFERASE1 to Regulate Rapid Responses to Sugar.Plant physiology · 2019Article
- Transcriptome and metabolome reveal distinct carbon allocation patterns during internode sugar accumulation in different sorghum genotypes.Plant biotechnology journal · 2019Article
- Common metabolic networks contribute to carbon sink strength of sorghum internodes: implications for bioenergy improvement.Biotechnology for biofuels · 2019Article
- Transcriptional Regulation of the Glucose-6-Phosphate/Phosphate Translocator 2 Is Related to Carbon Exchange Across the Chloroplast Envelope.Frontiers in plant science · 2019Article
- Effects of Nitrogen Level during Seed Production on Wheat Seed Vigor and Seedling Establishment at the Transcriptome Level.International journal of molecular sciences · 2018Article
- Article
- Transitioning to the Next Phase: The Role of Sugar Signaling throughout the Plant Life Cycle.Plant physiology · 2018Review
- Identifying novel fruit-related genes in Arabidopsis thaliana based on the random walk with restart algorithm.PloS one · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsGPT2, a glucose 6-phosphate/phosphate translocator, plays an important role in environmental sensing in mature leaves of Arabidopsis thaliana. Its expression has also been detected in arabidopsis seeds and seedlings. In order to examine the role of this protein early in development, germination and seedling growth were studied.
methodsGermination, greening and establishment of seedlings were monitored in both wild-type Arabidopsis thaliana and in a gpt2 T-DNA insertion knockout line. Seeds were sown on agar plates in the presence or absence of glucose and abscisic acid. Relative expression of GPT2 in seedlings was measured using quantitative PCR. KEY
resultsPlants lacking GPT2 expression were delayed (25-40 %) in seedling establishment, specifically in the process of cotyledon greening (rather than germination). This phenotype could not be rescued by glucose in the growth medium, with greening being hypersensitive to glucose. Germination itself was, however, hyposensitive to glucose in the gpt2 mutant.
conclusionsThe expression of GPT2 modulates seedling development and plays a crucial role in determining the response of seedlings to exogenous sugars during their establishment. This allows us to conclude that endogenous sugar signals function in controlling germination and the transition from heterotrophic to autotrophic growth, and that the partitioning of glucose 6-phosphate, or related metabolites, between the cytosol and the plastid modulates these developmental responses.
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