ArticleJournal of children's orthopaedics2014
Kingella kingae septic arthritis in children: recognising an elusive pathogen.
Article in Journal of children's orthopaedics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 64 citations in OpenAlex.
- Decision-making after joint aspiration: C-reactive protein and synovial white blood cell count as laboratory indicators for surgical joint lavage in pediatric septic arthritis.BMC musculoskeletal disorders · 2026Article
- Cytokine-mediated pathophysiology of equine and human joint disease: mechanisms, biomarkers, and therapeutic targets.Frontiers in veterinary science · 2026Review
- Fastidious or rarely isolated gram-negative rods with a particular focus onClinical microbiology reviews · 2025Review
- Ten-Year Experience with Native Joint Septic Arthritis: A Retrospective Cohort Study from a Tertiary Center.Journal of clinical medicine · 2025Article
- The Stealth and Potentially Fatal Nature ofOpen forum infectious diseases · 2025Review
- Joint fluid multi-omics improves diagnostic confidence during evaluation of children with presumed septic arthritis.Pediatric rheumatology online journal · 2025Article
- Article
- Clinical and ultrasound features of 46 children with suppurative osteoarthritis: experience from two centers.Journal of orthopaedic surgery and research · 2024Article
- Bacteriological diagnosis of osteoarticular infections caused byFrontiers in pediatrics · 2024Review
- Chimeric vaccine design against the conserved TonB-dependent receptor-like β-barrel domain from the outer membrane tbpA and hpuB proteins ofFrontiers in molecular biosciences · 2023Article
- The Past, Present, and Future ofDiagnostics (Basel, Switzerland) · 2022Review
- Use of 6 Nucleotide Length Words to Study the Complexity of Gene Sequences from Different Organisms.Entropy (Basel, Switzerland) · 2022Article
- Review
- Comparison of Microorganism Detection and Time to Positivity in Pediatric and Standard Media from Three Major Commercial Continuously Monitored Blood Culture Systems.Journal of clinical microbiology · 2021Article
- Pediatric Septic Arthritis of the Knee Due to a Multi-SensitiveChildren (Basel, Switzerland) · 2021Article
- Native joint septic arthritis due toIDCases · 2021Article
- Sonography of musculoskeletal infection in children.Ultrasound (Leeds, England) · 2020Review
- Pseudo paralysis of the shoulder and increased C-reactive protein are predictive factors for septic shoulder in children superior to other clinical symptoms: a retrospective case series of 25 patients.Journal of children's orthopaedics · 2020Review
- Systematic Review ofPediatric health, medicine and therapeutics · 2020Review
- A prospective study of screening for musculoskeletal pathology in the child with a limp or pseudoparalysis using erythrocyte sedimentation rate, C-reactive protein and MRI.Journal of children's orthopaedics · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeKingella kingae is an increasingly identified cause of musculoskeletal infections in young children. We report our experience with a recently developed polymerase chain reaction (PCR) method and review the clinical course of children diagnosed with K. kingae septic arthritis in a tertiary referral paediatric hospital.
methodsAll positive cases of K. kingae identified by PCR analysis of synovial fluid from August 2010 until July 2013 were included. A chart review was undertaken to determine history, presentation and management.
results27 Children (14 male, 13 female) had PCR positive synovial fluid samples for K. kingae with median age of 19 months (range 4 months to 5 years 3 months). The sites of infection were knee (17 cases), hip (2 cases), ankle (5 cases), shoulder (2 cases) and elbow. The median temperature on presentation was 37.1 °C, median peripheral white blood cell count 12.4 (9.9-13.8) × 10(9)/L, erythrocyte sedimentation rate 55 (48-60) mm/h and C-reactive protein 24 (8-47) mg/L. The median synovial fluid white cell count was 21.8 (16.7-45.0) × 10(9)/L. Routine cultures identified K. kingae in only two synovial fluid samples. Two samples were additionally positive for Staphylococcus aureus.
conclusionsKingella kingae is a significant cause of septic arthritis in young children. The authors recommend maintaining a high index of suspicion in young children presenting with joint inflammation, especially if indices of infection are mild. It appears likely that children historically treated with antibiotics for "culture negative" septic arthritis were infected with K. kingae. PCR techniques for detection of K. kingae should be encouraged.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.