Evidence map›Paper›PMID 24488838›Full record

Trial reportThe International journal of eating disorders2014

Confronting fear using exposure and response prevention for anorexia nervosa: A randomized controlled pilot study.

Joanna E Steinglass, Anne Marie Albano, H Blair Simpson, Yuanjia Wang, Jingjing Zou, Evelyn Attia, B Timothy Walsh

2 registry-linked trialsAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in The International journal of eating disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 55 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 3 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03712748 nacompletednot on this mapstarted 2016, after this paper: background citation

Imaginal Exposure I Online Study

TypeinterventionalSponsorUniversity of LouisvilleRan2016 to 2020Enrolled208ConditionsEating Disorder, Exposure, Anorexia Nervosa, Bulimia NervosaArmsImaginal Exposure therapy
NCT03934697 nacompletednot on this mapstarted 2017, after this paper: background citation

In-Vivo Treatment for Imaginal Exposure Therapy

TypeinterventionalSponsorUniversity of LouisvilleRan2017 to 2022Enrolled43ConditionsEating Disorder, Anorexia Nervosa, Bulimia Nervosa, ExposureArmsimaginal exposure therapy
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 3 syntheses or guidelines pooled it, 157 citations in OpenAlex.

  1. Pooled it
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  4. Trial
  5. Optimizing relapse prevention and changing habits (REACH+) in anorexia nervosa.The International journal of eating disorders · 2022
    Trial
  6. Trial
  7. Article
  8. Recovery From Anorexia Nervosa: A Concept Analysis.Journal of advanced nursing · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Joanna E SteinglassColumbia University, 622 West 168th Street, New York, New York; New York State Psychiatric Institute, 1051 Riverside Drive, New York, New York.
Anne Marie Albano
H Blair Simpson
Yuanjia Wang
Jingjing Zou
Evelyn Attia
B Timothy Walsh
New York Psychoanalytic Society and Institute · USColumbia University · USNew York State Psychiatric Institute

Funding

Cognitive Neuroscience of Anorexia NervosaK23MH076195 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STEINGLASS, JOANNA E · 2007 to 2011
$886k
Enhancing Patient-Oriented Research and Training in OCDK24MH091555 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SIMPSON, HELEN BLAIR · 2010 to 2014
$742k
Addressing Fear of Food in Anorexia NervosaR01MH082736 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI STEINGLASS, JOANNA E · 2007 to 2009
$740k
NIMH NIH HHS K23 MH076195NIMH NIH HHS K23MH076195-02NIMH NIH HHS K24 MH 091555NIMH NIH HHS K24 MH091555NIMH NIH HHS R01 MH082736NIMH NIH HHS R01MH08273602
6 · The paper itself

Abstract

objectiveAnorexia nervosa (AN) is a severe illness with high rates of relapse. Exposure and Response Prevention for AN (AN-EXRP) is a new approach that specifically addresses maladaptive eating behavior by targeting eating-related fear and anxiety. The aim of this study was to evaluate AN-EXRP as an adjunctive strategy to improve eating behavior during weight restoration, at a pivotal moment when treatment goals shift toward relapse prevention.

methodA randomized controlled trial was conducted to compare AN-EXRP with a comparison condition, Cognitive Remediation Therapy (CRT). Hospitalized patients with AN (n = 32) who had achieved weight restoration to a BMI > 18.5 kg/m(2) received 12 sessions of either AN-EXRP or CRT. Outcome was assessed by change in caloric intake in an objective assessment of eating behavior.

resultsThe average test meal caloric intake of participants who received AN-EXRP increased from 352 ± 263 kcal at baseline to 401 ± 215 kcal post-treatment, while that of participants who received CRT decreased from 501 ± 232 kcal at baseline to 424 ± 221 kcal post-treatment [t(28) = 2.5, p = .02]. Improvement in intake was significantly associated with improvement in eating-related anxiety (Spearman's ρ = 0.40, p = .03). DISCUSSION: These data demonstrate that AN-EXRP, compared to a credible comparison intervention, is associated with better caloric intake in a laboratory meal over time in AN. Additional studies are required to determine whether incorporation of these techniques into a longer treatment program leads to enduring and clinically significant change.

Indexed as

Cognitive Behavioral TherapyEnergy IntakeFearImplosive TherapyAdultAnorexia NervosaAnxietyBody WeightFeeding BehaviorFemaleHumansPilot ProjectsResearch Designanorexia nervosaanxietycognitive behavior therapycontrolled trialeating disordersexposure and response preventionexposure therapypsychotherapyrandomized trialtreatment

Identifiers

PMID24488838
PMCPMC3927538
OpenAlexW2171611171

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.