ArticlePediatrics2014
Dietary sodium, adiposity, and inflammation in healthy adolescents.
Article in Pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
76 citing papers in PubMed, 3 syntheses or guidelines pooled it, 136 citations in OpenAlex.
- Impact of Dietary Patterns on Migraine Management: Mechanisms of Action and Recent Literature Insights.Brain and behavior · 2025Pooled it
- Associations of Dietary Intake on Biological Markers of Inflammation in Children and Adolescents: A Systematic Review.Nutrients · 2021Pooled it
- The Science of Salt: A Regularly Updated Systematic Review of Salt and Health Outcomes (August to November 2015).Journal of clinical hypertension (Greenwich, Conn.) · 2016Pooled it
- Association of dietary inflammatory index and Chinese healthy eating index with abdominal obesity in kidney transplant recipients.Asia Pacific journal of clinical nutrition · 2026Article
- 2020-2025 Dietary Guidelines for Americans in Pregnancy: Adherence Shortfalls and Associations with Gestational Weight Gain.The Journal of nutrition · 2026Article
- Article
- Perinatal Exposure of Dams to a High Salt Diet Impaired Vascular Function and Elevated Biomarkers of Inflammation in the Offspring.Clinical Medicine Insights. Cardiology · 2025Article
- Article
- A study on the consumer behavior and attitude toward low-sodium convenience store foods.Nutrition research and practice · 2024Article
- Moderating effect of a sodium-rich diet on the association between long-term exposure to fine particulate matter and blood lipids in children and adolescents.BMC pediatrics · 2024Article
- Intermuscular adipose tissue accumulation is associated with higher tissue sodium in healthy individuals.Physiological reports · 2024Article
- Sodium intake: a double-edged sword wielded by the brain.Science China. Life sciences · 2024Article
- Impact of high-salt diet in health and diseases and its role in pursuit of cancer immunotherapy by modulating gut microbiome.Journal of family medicine and primary care · 2024Review
- Association between Urinary Sodium Excretion and Body Fat in School-Aged Children: Insights from the ARIA Study.Nutrients · 2024Article
- Inflammatory index score in children: its relationship with neophobia, dietary quality and anthropometric measurements.BMC public health · 2024Article
- Small intestinal microbiota composition altered in obesity-T2DM mice with high salt fed.Scientific reports · 2023Article
- Article
- Review
- Low-Grade Inflammation and Role of Anti-Inflammatory Diet in Childhood Obesity.International journal of environmental research and public health · 2023Review
- Downregulation of inflammatory erectile dysfunction byToxicology reports · 2023Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesTo determine the relationships of sodium intake with adiposity and inflammation in healthy adolescents.
methodsA cross-sectional study involved 766 healthy white and African American adolescents aged 14 to 18 years. Dietary sodium intake was estimated by 7-day 24-hour dietary recall. Percent body fat was measured by dual-energy x-ray absorptiometry. Subcutaneous abdominal adipose tissue and visceral adipose tissue were assessed using magnetic resonance imaging. Fasting blood samples were measured for leptin, adiponectin, C-reactive protein, tumor necrosis factor-α, and intercellular adhesion molecule-1.
resultsThe average sodium intake was 3280 mg/day. Ninety-seven percent of our adolescents exceeded the American Heart Association recommendation for sodium intake. Multiple linear regressions revealed that dietary sodium intake was independently associated with body weight (β = 0.23), BMI (β = 0.23), waist circumference (β = 0.23), percent body fat (β = 0.17), fat mass (β = 0.23), subcutaneous abdominal adipose tissue (β = 0.25), leptin (β = 0.20), and tumor necrosis factor-α (β = 0.61; all Ps < .05). No relation was found between dietary sodium intake and visceral adipose tissue, skinfold thickness, adiponectin, C-reactive protein, or intercellular adhesion molecule-1. All the significant associations persisted after correction for multiple testing (all false discovery rates < 0.05).
conclusionsThe mean sodium consumption of our adolescents is as high as that of adults and more than twice the daily intake recommended by the American Heart Association. High sodium intake is positively associated with adiposity and inflammation independent of total energy intake and sugar-sweetened soft drink consumption.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.