ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2014
Neuroimaging the epileptogenic process.
Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Post-Stroke Epileptogenesis as a Dynamic Network Process: State-Dependent Biomarkers, Longitudinal Monitoring, and the Concept of an Irritable Brain State.International journal of molecular sciences · 2026Review
- Multiomic Analyses Reveal Brainstem Metabolic Changes in a Mouse Model of Dravet Syndrome.Cells · 2025Article
- Mitochondrial respiration defects in lymphoblast cell lines from patients with Dravet syndrome.Epilepsia · 2025Article
- Neuroglia and brain energy metabolism.Handbook of clinical neurology · 2025Review
- Radiolabeling of Zonisamide for a Diagnostic Perspective.Current radiopharmaceuticals · 2024Article
- The metabolic basis of epilepsy.Nature reviews. Neurology · 2022Review
- Automated fusion of multimodal imaging data for identifying epileptogenic lesions in patients with inconclusive magnetic resonance imaging.Human brain mapping · 2021Article
- Enhancing glucose metabolism via gluconeogenesis is therapeutic in a zebrafish model of Dravet syndrome.Brain communications · 2021Article
- Article
- Neuroimaging Biomarkers of Experimental Epileptogenesis and Refractory Epilepsy.International journal of molecular sciences · 2019Review
- Multimodal quantitative magnetic resonance imaging analysis with individualized postprocessing in patients with drug-resistant focal epilepsy and conventional visual inspection negative for epileptogenic lesions.Clinics (Sao Paulo, Brazil) · 2019Article
- Hungry Neurons: Metabolic Insights on Seizure Dynamics.International journal of molecular sciences · 2017Review
- Early tissue damage and microstructural reorganization predict disease severity in experimental epilepsy.eLife · 2017Article
- Advanced structural multimodal imaging of a patient with subcortical band heterotopia.Epilepsia open · 2016Article
- Audit of practice in sudden unexpected death in epilepsy (SUDEP) post mortems and neuropathological findings.Neuropathology and applied neurobiology · 2016Article
- Behavioral, blood, and magnetic resonance imaging biomarkers of experimental mild traumatic brain injury.Scientific reports · 2016Article
- Computational analysis in epilepsy neuroimaging: A survey of features and methods.NeuroImage. Clinical · 2016Review
- Neurology--the next 10 years.Nature reviews. Neurology · 2015Review
- Sodium selenate reduces hyperphosphorylated tau and improves outcomes after traumatic brain injury.Brain : a journal of neurology · 2015Article
- Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epilepsy is one of the most common chronic neurological conditions worldwide. Anti-epileptic drugs (AEDs) can suppress seizures, but do not affect the underlying epileptic state, and many epilepsy patients are unable to attain seizure control with AEDs. To cure or prevent epilepsy, disease-modifying interventions that inhibit or reverse the disease process of epileptogenesis must be developed. A major limitation in the development and implementation of such an intervention is the current poor understanding, and the lack of reliable biomarkers, of the epileptogenic process. Neuroimaging represents a non-invasive medical and research tool with the ability to identify early pathophysiological changes involved in epileptogenesis, monitor disease progression, and assess the effectiveness of possible therapies. Here we will provide an overview of studies conducted in animal models and in patients with epilepsy that have utilized various neuroimaging modalities to investigate epileptogenesis.
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Registered trials
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