Evidence map›Paper›PMID 24488548›Full record

ReviewCurrent oncology reports2014

Counseling the patient with potentially HPV-related newly diagnosed head and neck cancer.

John P Finnigan, Andrew G Sikora

Abstract readReview
In one paragraph

Review in Current oncology reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John P FinniganDepartment of Otolaryngology, Icahn School of Medicine at Mount Sinai, New York, USA, john.finnigan@mssm.edu.
Andrew G Sikora

Funding

TARGETING INOS TO INHIBIT MYELOID-DERIVED SUPPRESSOR CELLS (MDSC) IN MELANOMAK08CA154963 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SIKORA, ANDREW · 2011 to 2015
$674k
Role of Activated EGFR and COX-2 in Metastasis and Escape from Tumor DormancyR03DE021741 · NIDCR · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SIKORA, ANDREW · 2011 to 2012
$254k
NCI NIH HHS K08 CA154963NCI NIH HHS L30 CA154165NIDCR NIH HHS L30 DE022953NIDCR NIH HHS R03 DE021741
6 · The paper itself

Abstract

The recent emergence of a clinically distinct subset of head and neck cancers (HNC) caused by infection with the human papillomavirus (HPV) necessitates critical reevaluation of the existing counseling paradigm for patients with newly diagnosed HNC. Herein we propose a structural framework for patient counseling in which HPV testing is incorporated and the impact of HPV-status is discussed in the context of multiple medical and psychosocial domains. We strive to maintain a balance between making recommendations based on the best available scientific evidence and acknowledgment of uncertainty for both patients and providers. We anticipate that both the standard-of-care diagnostic workup and treatment, and counseling guidelines for these patients will change rapidly in the years ahead, as data from ongoing and planned prospective clinical trials become available.

Indexed as

Carcinoma, Squamous CellCounselingEvidence-Based MedicineHead and Neck NeoplasmsHumansPapillomaviridaePapillomavirus InfectionsPractice Guidelines as TopicSquamous Cell Carcinoma of Head and Neck

Identifiers

PMID24488548
PMCPMC4100323

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.