Evidence map›Paper›PMID 24488514›Full record

ArticleAmerican journal of epidemiology2014

Invited commentary: Some advantages of the relative excess risk due to interaction (RERI)--towards better estimators of additive interaction.

Tyler J VanderWeele, Stijn Vansteelandt

Abstract readComment
In one paragraph

Article in American journal of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  12. Excess mortality after hip fracture: fracture or pre-fall comorbidity?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Tyler J VanderWeele
Stijn Vansteelandt

Funding

Statistical Methods for Analysis of Massive Genetic and Genomic Data in Cancer ResearchR35CA197449 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI XIHONG LIN · 2015 to 2026
$10.9M
Statistical Methods for the Spatio-Temporal Assessment of Social Disparities in CancerP01CA134294 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI HANEUSE, SEBASTIEN, HERNAN, MIGUEL · 2008 to 2017
$6.8M
Theory and methods for sufficient cause interactionsR01ES017876 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI VANDERWEELE, TYLER · 2010 to 2014
$1.2M
Theory and methods for interactionR56ES017876 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI TCHETGEN TCHETGEN, ERIC JOEL, VANDERWEELE, TYLER · 2016 to 2016
$150k
NCI NIH HHS P01 CA134294NCI NIH HHS R35 CA197449NIEHS NIH HHS ES017876NIEHS NIH HHS R01 ES017876
6 · The paper itself

Abstract

In the accompanying commentary, Rose and van der Laan (Am J Epidemiol. 2014;179(6):663-669) criticize the relative excess risk due to interaction (RERI) measure, the use of additive interaction, and the weighting approach we developed to assess RERI with case-control data. In this commentary, we note some of the advantages of using additive measures of interaction, such as RERI, in making decisions about targeting interventions toward certain subgroups and in assessing mechanistic interaction. We discuss the relationship between Rose and van der Laan's estimator for case-control data and the one we had previously proposed. We also develop a new doubly robust estimator for determining the RERI with case-control data when the prevalence or incidence of the outcome is known.

Indexed as

Case-Control StudiesCausalityData Interpretation, StatisticalEpidemiologic Research DesignHumansadditive interactioncase-control studiesdoubly robust estimatorsubgroup analysissynergism

Identifiers

PMID24488514
PMCPMC3939844

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.