Evidence map›Paper›PMID 24488107›Full record

ArticleParasitology research2014

The antitrichomonal efficacy of garlic and metronidazole against Trichomonas gallinae infecting domestic pigeons.

Sh A Seddiek, Mohamed M El-Shorbagy, Hanem F Khater, Ali M Ali

Abstract read
PubMed Publisher
In one paragraph

Article in Parasitology research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Prevalence ofArchives of Razi Institute · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Novel Pesticidal Efficacy ofPlants (Basel, Switzerland) · 2022
    Article
  11. Anti-Frontiers in veterinary science · 2022
    Article
  12. Veterinary research forum : an international quarterly journal · 2021
    Article
  13. Article
  14. Activity of Thioallyl Compounds From Garlic AgainstFrontiers in cellular and infection microbiology · 2018
    Article
  15. Iranian journal of veterinary research · 2017
    Article
  16. Article
  17. Article
  18. Article
  19. Properties of Compounds Citral and Geraniol onIranian journal of parasitology
    Article
  20. Avicenna journal of phytomedicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sh A SeddiekAvian Diseases Department, Animal Health Research Institute Benha Branch, Benha, 13111, Egypt.
Mohamed M El-Shorbagy
Hanem F Khater
Ali M Ali
Benha University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trichomonas gallinae is the causative agent of canker in pigeon. This work was carried out to investigate in the vitro and in vivo efficacy of aqueous water extract of garlic (AGE) on the growth of T. gallinae infecting pigeons compared to those of metronidazole (MTZ). MTZ and AGE were added, at different concentrations, to glucose-serum broth medium containing 1 × 10(4) trophozoites/ml. In the in vivo experiment, 48 squabs were grouped into four groups. The first group (gr. I) was not infected and not treated. Each squab of the other group was infected with 1 × 10(4) trophozoites. The second group (gr. II) was infected and not treated. On day 0, the third group (gr. III) was treated with MTZ (50 mg/kg BW) and the fourth group (gr. IV) was treated with AGE (200 mg/kg BW) for seven successive days in drinking water. In vitro study revealed that the MLC, 24, 48, and 72 h post treatment were 50, 25, and 12.5 μg/ml, respectively, for MTZ and 75, 50, and 50 mg/ml, respectively, for AGE. Garlic (200 mg/kg BW) had the highest antitrichomonal effect and shortened course of treatment of pigeons from 7 days in gr. III to 5 days. Squabs in gr. II suffered from macrocytic hypochromic anemia, whereas squabs in grs. III and IV showed normal blood pictures. Serum total protein, albumin, and globulin were increased, whereas AST, ALT, and the total cholesterol were decreased in grs. III and IV when compared to those of gr. II. Pigeons protected with AGE showed increased body weight and reduced mortality percentage than the other groups. Our results indicated that garlic may be a promising phytotherapeutic agent for protection against trichomoniasis in pigeons.

Indexed as

AnimalsAntitrichomonal AgentsBird DiseasesColumbidaeGarlicMetronidazolePlant ExtractsTrichomonasTrichomonas InfectionsTrophozoitesAntitrichomonal AgentsMetronidazolePlant Extracts

Identifiers

PMID24488107
OpenAlexW2473663174

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.