ReviewOrganogenesis
Future prospects for tissue engineered lung transplantation: decellularization and recellularization-based whole lung regeneration.
Review in Organogenesis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Tools of the trade: leveraging 3DFrontiers in pharmacology · 2026Review
- Decellularized extracellular matrix biomaterials for regenerative therapies: Advances, challenges and clinical prospects.Bioactive materials · 2024Review
- Adipose-Derived Mesenchymal Stem Cells Attenuate Immune Reactions Against Pig Decellularized Bronchi Engrafted into Rat Tracheal Defects.Organogenesis · 2023Article
- Epidemiology and Long-Term Outcomes in Thoracic Transplantation.Journal of cardiovascular development and disease · 2023Review
- Bioengineering and Clinical Translation of Human Lung and its Components.Advanced biology · 2023Review
- Differentiation of human induced pluripotent stem cells into functional lung alveolar epithelial cells in 3D dynamic culture.Frontiers in bioengineering and biotechnology · 2023Article
- Lung organoids: current strategies for generation and transplantation.Cell and tissue research · 2022Review
- Emerging Paradigms in Bioengineering the Lungs.Bioengineering (Basel, Switzerland) · 2022Review
- Bioengineering lungs: An overview of current methods, requirements, and challenges for constructing scaffolds.Frontiers in bioengineering and biotechnology · 2022Review
- Cell Inertia: Predicting Cell Distributions in Lung Vasculature to Optimize Re-endothelialization.Frontiers in bioengineering and biotechnology · 2022Article
- Applications of Biomaterials in 3D Cell Culture and Contributions of 3D Cell Culture to Drug Development and Basic Biomedical Research.International journal of molecular sciences · 2021Review
- Lung Microvascular Niche, Repair, and Engineering.Frontiers in bioengineering and biotechnology · 2020Review
- Induction of lung-like cells from mouse embryonic stem cells by decellularized lung matrix.Biochemistry and biophysics reports · 2018Article
- In Vivo Performance of Decellularized Vascular Grafts: A Review Article.International journal of molecular sciences · 2018Review
- Sodium hydroxide based non-detergent decellularizing solution for rat lung.Organogenesis · 2018Article
- "Tissue Papers" from Organ-Specific Decellularized Extracellular Matrices.Advanced functional materials · 2017Article
- Transplantation of bioengineered rat lungs recellularized with endothelial and adipose-derived stromal cells.Scientific reports · 2017Article
- Functional vascularized lung grafts for lung bioengineering.Science advances · 2017Article
- Lung regeneration: steps toward clinical implementation and use.Current opinion in anaesthesiology · 2017Review
- Revascularization of decellularized lung scaffolds: principles and progress.American journal of physiology. Lung cellular and molecular physiology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The shortage of donor lungs for transplantation causes a significant number of patient deaths. The availability of laboratory engineered, functional organs would be a major advance in meeting the demand for organs for transplantation. The accumulation of information on biological scaffolds and an increased understanding of stem/progenitor cell behavior has led to the idea of generating transplantable organs by decellularizing an organ and recellularizing using appropriate cells. Recellularized solid organs can perform organ-specific functions for short periods of time, which indicates the potential for the clinical use of engineered solid organs in the future. The present review provides an overview of progress and recent knowledge about decellularization and recellularization-based approaches for generating tissue engineered lungs. Methods to improve decellularization, maturation of recellularized lung, candidate species for transplantation and future prospects of lung bioengineering are also discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.