Evidence map›Paper›PMID 24487062›Full record

ReviewCurrent opinion in chemical biology2014

Chemistry of natural glycan microarrays.

Xuezheng Song, Jamie Heimburg-Molinaro, Richard D Cummings, David F Smith

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in chemical biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 63 citations in OpenAlex.

  1. Heparan sulfate glycomimeticsChemical science · 2023
    Article
  2. Article
  3. Review
  4. Glycan Array Technology.Advances in biochemical engineering/biotechnology · 2021
    Article
  5. 130 years of Plant Lectin Research.Glycoconjugate journal · 2020
    Review
  6. Review
  7. Review
  8. Review
  9. Tools for generating and analyzing glycan microarray data.Beilstein journal of organic chemistry · 2020
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Microbe-focused glycan array screening platform.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xuezheng SongDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, United States. Electronic address: xsong2@emory.edu.
Jamie Heimburg-MolinaroDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, United States.
Richard D CummingsDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, United States.
David F SmithDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, United States.
Emory University · US

Funding

Overall Priority Score P41GM103694 · NIGMS · EMORY UNIVERSITY · PI CUMMINGS, RICHARD D · 2013 to 2018
$6.9M
Shotgun Glycomics: Linking Glycan Structure and FunctionR01GM085448 · NIGMS · EMORY UNIVERSITY · PI SMITH, DAVID FLETCHER · 2008 to 2011
$2.3M
TOTAL SYNTHESIS OF (+)-PEDERINF32GM010369 · NIGMS · YALE UNIVERSITY · PI ZELLE, ROBERT E · 1985 to 1985
–
NIGMS NIH HHS GM085448NIGMS NIH HHS P41GM10369NIGMS NIH HHS P41 GM103694NIGMS NIH HHS R01 GM085448
6 · The paper itself

Abstract

Glycan microarrays have become indispensable tools for studying protein-glycan interactions. Along with chemo-enzymatic synthesis, glycans isolated from natural sources have played important roles in array development and will continue to be a major source of glycans. N-glycans and O-glycans from glycoproteins, and glycans from glycosphingolipids (GSLs) can be released from corresponding glycoconjugates with relatively mature methods, although isolation of large numbers and quantities of glycans is still very challenging. Glycosylphosphatidylinositol (GPI) anchors and glycosaminoglycans (GAGs) are less represented on current glycan microarrays. Glycan microarray development has been greatly facilitated by bifunctional fluorescent linkers, which can be applied in a 'Shotgun Glycomics' approach to incorporate isolated natural glycans. Glycan presentation on microarrays may affect glycan binding by GBPs, often through multivalent recognition by the GBP.

Indexed as

AnimalsBiological ProductsDatabases, GeneticGlycomicsGlycoproteinsGlycosphingolipidsHumansPolysaccharidesBiological ProductsGlycoproteinsGlycosphingolipidsPolysaccharides

Identifiers

PMID24487062
PMCPMC3940340
OpenAlexW2084371565

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.