Evidence map›Paper›PMID 24487051›Full record

Observational studyAmerican journal of ophthalmology2014

Whole eye axial biometry during accommodation using ultra-long scan depth optical coherence tomography.

Jianguang Zhong, Aizhu Tao, Zhe Xu, Hong Jiang, Yilei Shao, Huicheng Zhang, Che Liu, Jianhua Wang

Abstract readObservational Study
In one paragraph

Observational study in American journal of ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
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  12. Comparison of anterior segment and lens biometric measurements in patients with cataract.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Article
  13. Article
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  16. Repeatability assessment of anterior segment biometric measurements under accommodative and nonaccommodative conditions using an anterior segment OCT.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018
    Article
  17. Ocular anatomic changes for different accommodative demands using swept-source optical coherence tomography: a pilot study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jianguang ZhongBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida; Hangzhou First People's Hospital, Zhejiang, China.
Aizhu TaoBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida; School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, China.
Zhe XuBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida; School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, China.
Hong JiangHangzhou First People's Hospital, Zhejiang, China.
Yilei ShaoBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida; School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, China.
Huicheng ZhangHangzhou First People's Hospital, Zhejiang, China.
Che LiuDepartment of Biomedical Engineering, University of Miami, Miami, Florida.
Jianhua WangBascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida. Electronic address: jwang3@med.miami.edu.

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Victor L Perez · 2004 to 2026
$12.2M
Advanced imaging for diabetic retinopathyR01EY020607 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CABRERA-DEBUC, DELIA · 2011 to 2015
$2.0M
Characterization of Tear DynamicsR03EY016420 · NEI · UNIVERSITY OF ROCHESTER · PI WANG, JIANHUA · 2005 to 2007
$454k
Optical coherence tomography equipped wavefront system for studying accommodationR21EY021336 · NEI · NEW ENGLAND COLLEGE OF OPTOMETRY · PI HE, JI CHANG · 2012 to 2013
$395k
Magnetomotive optical coherence tomography for molecular imaging of the eyeR21EY021012 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI WANG, JIANHUA · 2010 to 2010
$228k
NEI NIH HHS EY020607SNEI NIH HHS EY021012NEI NIH HHS EY021336NEI NIH HHS P30 EY014801NEI NIH HHS R01 EY020607NEI NIH HHS R03 EY016420NEI NIH HHS R21 EY021012NEI NIH HHS R21 EY021336
6 · The paper itself

Abstract

purposeTo investigate changes of whole eye axial biometry during accommodation using ultra-long scan depth optical coherence tomography (UL-OCT).

designProspective, observational case series.

methodsTwenty-one adult subjects were enrolled. Using UL-OCT, the left eye of each subject was imaged with relaxed diopters (0 D) and accommodative stimuli (+6 D). Full eye biometry included central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness, vitreous length, and axial length (AL).

resultsDuring accommodation (+6 D), the axial biometry of the whole eye changed significantly. Compared to the rest state, ACD at the accommodative state decreased significantly from 3.128 ± 0.305 mm to 2.961 ± 0.298 mm (paired t test, P < .001). The lens thickness increased significantly from 3.723 ± 0.237 mm to 3.963 ± 0.234 mm (P < .001). The vitreous length decreased significantly from 17.129 ± 0.864 mm to 17.057 ± 0.848 mm (P < .001). AL was 24.519 ± 0.917 mm at the rest state and increased to 24.545 ± 0.915 mm with +6 D accommodation stimulus. The elongated AL of 26.1 ± 13.4 μm between the rest and accommodative states was significant (P < .001).

conclusionsDuring accommodation, whole eye axial biometry changed, including a decrease in ACD and vitreous length and an increase in lens thickness and AL. UL-OCT provides an alternative method that is suitable for full eye biometry during accommodation.

Indexed as

Accommodation, OcularAdultAnterior ChamberAxial Length, EyeBiometryCorneaFemaleHumansLens, CrystallineMaleProspective StudiesTomography, Optical CoherenceVitreous BodyYoung Adult

Identifiers

PMID24487051
PMCPMC4040283

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.