ArticleVeterinary microbiology2014
Multidrug-resistant Escherichia coli from canine urinary tract infections tend to have commensal phylotypes, lower prevalence of virulence determinants and ampC-replicons.
Article in Veterinary microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Parameters for one health genomic surveillance of Escherichia coli from Australia.Nature communications · 2025Article
- Detection of biofilm formation and antibiotics resistance ofOpen veterinary journal · 2024Article
- Multidrug resistance in pathogenicFrontiers in veterinary science · 2024Article
- Article
- Adherence of UropathogenicJournal of veterinary research · 2023Article
- Genomic traits of multidrug resistant enterotoxigenicFrontiers in microbiology · 2023Article
- Epidemiology of companion animal AMR in the United States of America: filling a gap in the one health approach.Frontiers in public health · 2023Article
- Transmission ofMicroorganisms · 2022Article
- Molecular ecology and risk factors for third-generation cephalosporin-resistant Escherichia coli carriage by dogs living in urban and nearby rural settings.The Journal of antimicrobial chemotherapy · 2022Article
- Fecal Shedding of Multidrug ResistantAntibiotics (Basel, Switzerland) · 2022Article
- Molecular Characteristics of Extraintestinal PathogenicMicroorganisms · 2020Article
- Broad-Spectrum Cephalosporin-Resistant and/or Fluoroquinolone-ResistantAntibiotics (Basel, Switzerland) · 2020Article
- Occurrence and Predictors of Bacterial Respiratory Tract Infections and Antimicrobial Resistance Among Isolates From Dogs Presented With Lower Respiratory Tract Infections at a Referral Veterinary Hospital in South Africa.Frontiers in veterinary science · 2020Article
- PathogenicFrontiers in microbiology · 2020Article
- Diversity, Virulence, and Clinical Significance of Extended-Spectrum β-Lactamase- and pAmpC-ProducingFrontiers in microbiology · 2019Article
- Characterization of avian pathogenic Escherichia coli isolated from free-range helmeted guineafowl.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2018Article
- Population Structure and Antimicrobial Resistance of Canine Uropathogenic Escherichia coli.Journal of clinical microbiology · 2018Article
- Antimicrobial resistance among Escherichia coli isolates from dogs presented with urinary tract infections at a veterinary teaching hospital in South Africa.BMC veterinary research · 2018Article
- Complete Genome Sequences of Two T4-Like Escherichia coli Bacteriophages.Genome announcements · 2018Article
- Increase in antimicrobial resistance and emergence of major international high-risk clonal lineages in dogs and cats with urinary tract infection: 16 year retrospective study.The Journal of antimicrobial chemotherapy · 2018Article
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Abstract
Multidrug-resistant Escherichia coli is an emerging clinical challenge in domestic species. Treatment options in many cases are limited. This study characterized MDR E. coli isolates from urinary tract infections in dogs, collected between 2002 and 2011. Isolates were evaluated in terms of β-lactamase production, phylogenetic group, ST type, replicon type and virulence marker profile. Comparisons were made with antibiotic susceptible isolates also collected from dogs with urinary tract infections. AmpC β-lactamase was produced in 67% of the MDR isolates (12/18). Of these, 8 could be specifically attributed to the CMY-2 gene. None of the isolates tested in either group expressed ESBLs. Phylo-group distribution was as expected in the susceptible isolates, with an over representation of the pathogenic B2 phylo-group (67%). In contrast, the phylogenetic background for the MDR group was mixed, with representation of commensal phylo-groups A and B1. The B2 phylo-group represented the smallest proportion (A, B1, B2 or D was 28%, 22%, 11% and 33%, respectively). Virulence marker profiles, evaluated using Identibac(®) microarray, discriminated between the two groups. Marker sequences for a core panel of virulence determinants were identified in most of the susceptible isolates, but not in most of the MDR isolates. These findings indicate that for MDR isolates, plasmid-mediated AmpC is an important resistance mechanism, and while still capable of causing clinical disease, there is evidence for a shift towards phylogenetic groups of reduced inferred virulence potential. There was no evidence of zoonotic potential in either the susceptible or MDR urinary tract isolates in this study.
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