Evidence map›Paper›PMID 24485449›Full record

ArticleCell2014

Sex-specific aging in flies, worms, and missing great-granddads.

Caleb E Finch, John Tower

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Caleb E FinchDavis School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA. Electronic address: cefinch@usc.edu.
John TowerDavis School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA. Electronic address: jtower@usc.edu.
University of Southern California · US

Funding

Timing of Menopausal Hormone Therapy across Perimenopause to Menopause Transition: Neuroimmune System in BrainP01AG026572 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Schantel Williams · 2006 to 2026
$53.7M
AGING-SPECIFIC GENE EXPRESSION IN DROSOPHILAR01AG011833 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TOWER, JOHN GERARD · 1994 to 2013
$2.8M
Aging and sensitivity to traffic-generated air pollutants in male and female miceR21AG040753 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FINCH, CALEB E · 2011 to 2012
$365k
NIA NIH HHS AG026572NIA NIH HHS AG040753NIA NIH HHS P01 AG026572NIA NIH HHS R01 AG011833NIA NIH HHS R21 AG040753
6 · The paper itself

Abstract

Two recent studies identify how sex-specific pheromonal factors in flies and worms alter lifespan through metabolic pathways that are shared with mammals. Sex differences in human lifespans imply nonautonomous effects modulated by sex-specific gene-environment interactions that could still include pheromonal mechanisms.

Indexed as

AgingLife ExpectancyModels, AnimalAnimalsFemaleGene-Environment InteractionHumansMaleSex Characteristics

Identifiers

PMID24485449
PMCPMC3988832
OpenAlexW2055020809

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.