Trial reportBMC psychiatry2014
Multidimensional family therapy decreases the rate of externalising behavioural disorder symptoms in cannabis abusing adolescents: outcomes of the INCANT trial.
Trial report in BMC psychiatry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Systemic therapy in children and adolescents with mental disorders: a systematic review and meta-analysis.BMC psychiatry · 2024Pooled it
- Psychosocial interventions for cannabis use disorder.The Cochrane database of systematic reviews · 2016Pooled it
- A pilot randomized controlled trial of an integrative psychotherapy incorporating an attachment-based approach for adolescents with cannabis use disorder (TIMCA).Addictive behaviors reports · 2026Article
- Measuring Outcomes in Evaluations of Interventions to Prevent Youth Crime and Violence: Challenges and Potential Solutions.Journal of prevention (2022) · 2026Article
- Cannabis use disorder: an overview of treatment approaches in Europe.European archives of psychiatry and clinical neuroscience · 2025Review
- Article
- An Equity-Focused Assessment of Evidence-Based Parenting Intervention Research.Clinical child and family psychology review · 2024Review
- Multidimensional Family Therapy for Justice-Involved Young Adults with Substance Use Disorders.The journal of behavioral health services & research · 2024Article
- Towards a New Dynamic Interaction Model of Adolescent CUD Manifestation, Prevention, and Treatment: A Narrative Review.Psychoactives · 2023Article
- Assessing the reliability and validity of the Risk-Need-Responsivity (RNR) program tool.Health & justice · 2022Article
- Multidimensional family therapy in adolescents with a cannabis use disorder: long-term effects on delinquency in a randomized controlled trial.Child and adolescent psychiatry and mental health · 2018Article
- Treating Mental Health and Substance Use Disorders in Adolescents: What Is on the Menu?Current psychiatry reports · 2017Review
- Family-Based Treatments for Adolescent Substance Use.Child and adolescent psychiatric clinics of North America · 2016Review
- Evidence-based Treatment Options in Cannabis Dependency.Deutsches Arzteblatt international · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 8 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUS-based trials have shown that Multidimensional Family Therapy (MDFT) not only reduces substance abuse among adolescents, but also decreases mental and behavioural disorder symptoms, most notably externalising symptoms. In the INCANT trial, MDFT decreased the rate of cannabis dependence among Western European youth. We now focus on other INCANT outcomes, i.e., lessening of co-morbidity symptoms and improvement of family functioning.
methodsINCANT was a randomised controlled trial comparing MDFT with individual therapy (IP) at and across sites in Berlin, Brussels, Geneva, The Hague, and Paris. We recruited 450 boys and girls aged 13 up to 18 years with a cannabis use disorder, and their parent(s), and followed them for 12 months. Mental and behavioural characteristics (classified as 'externalising' or 'internalising') and family conflict and cohesion were assessed.
resultsFrom intake through 12 months, MDFT and IP groups improved on all outcome measures. Models including treatment, site, and referral source showed that MDFT outperformed IP in reducing externalising symptoms.Adolescents were either self-referred to treatment (mostly on the initiative from people close to the teen) or referred under some measure of coercion by an external authority. These two groups reacted equally well to treatment.
conclusionsBoth MDFT and IP reduced the rate of externalising and internalising symptoms and improved family functioning among adolescents with a cannabis use disorder. MDFT outperformed IP in decreasing the rate of externalising symptoms. Contrary to common beliefs among therapists in parts of Western Europe, the 'coerced' adolescents did at least as well in treatment as the self-referred adolescents.MDFT shows promise as a treatment for both substance use disorders and externalising symptoms. TRIAL REGISTRATION ISRNCT: ISRCTN51014277.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.