Evidence map›Paper›PMID 24484314›Full record

SynthesisBMC geriatrics2014

Is the Timed Up and Go test a useful predictor of risk of falls in community dwelling older adults: a systematic review and meta-analysis.

Emma Barry, Rose Galvin, Claire Keogh, Frances Horgan, Tom Fahey

7 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC geriatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 7 registered trials, which are not on this map. Cited by 459 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
459citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05670314 nacompletednot on this mapstarted 2022, after this paper: background citation

Molecular Signatures of Endocannabinoid Induced Pain Relief in Humans: Lifestyle Interventions, Systemic and Localised Changes

TypeinterventionalSponsorUniversity of NottinghamRan2022 to 2025Enrolled117ConditionsOsteoarthritis, KneeArmsInulin Fibre supplement, Maltodextrin (Placebo), Exercise
NCT06074744 narecruitingnot on this mapstarted 2023, after this paper: background citation

Subsartorial Saphenous Nerve Block (SSNB) Versus Femoral Nerve Block (FNB) in Primary Total Knee Arthroplasty (TKA) Combined With Infiltration Between Popliteal Artery and Capsule of the Knee (IPACK) - Where Are the Benefits?

TypeinterventionalSponsorLuzerner KantonsspitalRan2023 to 2026Enrolled144ConditionsJoint Diseases, Joint PainArmsSSNB + IPACK, FNB + IPACK
NCT06175871 nacompletednot on this mapstarted 2024, after this paper: background citation

Development of a New Clinical Rehabilitation Approach for the Management of Elderly People With a Neuromusculoskeletal Disorder and a Risk of Falls: a Partnership Project Between UQAC and the Specialized Geriatric Services of CIUSSS-SLSJ

TypeinterventionalSponsorUniversité du Québec à ChicoutimiRan2024 to 2025Enrolled11ConditionsMusculoskeletal Diseases, Chronic Disease, Fall Patients, Aging ProblemsArmsOTAGO exercises
NCT06210828 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effectiveness of Telerehabilitation in Balance Training Program Among Elderly at Risk of Falling, a Randomized Controlled Trial

TypeinterventionalSponsorSiriraj HospitalRan2023 to 2025Enrolled48ConditionsPostural Balance, FallArmsTelerehabilitation, Control
NCT06648798 narecruitingnot on this mapstarted 2023, after this paper: background citation

LIMBER UniLeg: Rapid, On-demand, and Scaled-up Manufacturing of Customized Transtibial Prosthetic Legs for Amputees

TypeinterventionalSponsorLIMBER Prosthetics & Orthotics IncRan2023 to 2026Enrolled30ConditionsAmputation of Lower Limb, Prosthesis, Non-inferiority Trial of ProthesisArmsLimber Limb
NCT07296653 early_phase1recruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy of Prolotherapy in Acupoints in Chronic Non-specific Low Back Pain (cLBP) - A Randomized Control Trial

TypeinterventionalSponsorNational and Kapodistrian University of AthensRan2025 to 2027Enrolled60ConditionsChronic Non-specific Low Back PainArmsDextrose 15% and lidocaine 1% infiltration, Lidocaine 1% infiltration
NCT07362212 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Validity, Reliability, and Clinical Correlates of Virtual Reality Adaptations of the 4-meter Walk Test, Five Times Sit-to-stand Test, and Timed up and go Test in Older Adults

TypeobservationalSponsorSelcuk UniversityRan2026 to 2026Enrolled70ConditionsFunctional Mobility, Virtual Reality-Based Functional AssessmentArmsClinical Assessments
3 · Its place in the literature

Who cites it

459 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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399 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emma Barry
Rose GalvinHRB Centre for Primary Care research, Department of General Practice, Royal College of Surgeons in Ireland, 123 St, Stephens Green, Dublin 2, Republic of Ireland. rosegalvin@rcsi.ie.
Claire Keogh
Frances Horgan
Tom Fahey

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Timed Up and Go test (TUG) is a commonly used screening tool to assist clinicians to identify patients at risk of falling. The purpose of this systematic review and meta-analysis is to determine the overall predictive value of the TUG in community-dwelling older adults.

methodsA literature search was performed to identify all studies that validated the TUG test. The methodological quality of the selected studies was assessed using the QUADAS-2 tool, a validated tool for the quality assessment of diagnostic accuracy studies. A TUG score of ≥13.5 seconds was used to identify individuals at higher risk of falling. All included studies were combined using a bivariate random effects model to generate pooled estimates of sensitivity and specificity at ≥13.5 seconds. Heterogeneity was assessed using the variance of logit transformed sensitivity and specificity.

resultsTwenty-five studies were included in the systematic review and 10 studies were included in meta-analysis. The TUG test was found to be more useful at ruling in rather than ruling out falls in individuals classified as high risk (>13.5 sec), with a higher pooled specificity (0.74, 95% CI 0.52-0.88) than sensitivity (0.31, 95% CI 0.13-0.57). Logistic regression analysis indicated that the TUG score is not a significant predictor of falls (OR = 1.01, 95% CI 1.00-1.02, p = 0.05).

conclusionThe Timed Up and Go test has limited ability to predict falls in community dwelling elderly and should not be used in isolation to identify individuals at high risk of falls in this setting.

Indexed as

Accidental FallsActivities of Daily LivingResidence CharacteristicsAgedAged, 80 and overGeriatric AssessmentHumansMass ScreeningPredictive Value of TestsRisk FactorsTime Factors

Identifiers

PMID24484314
PMCPMC3924230

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.