Evidence map›Paper›PMID 24484215›Full record

ReviewExpert review of anti-infective therapy2014

Point of care diagnostics for sexually transmitted infections: perspectives and advances.

Charlotte Gaydos, Justin Hardick

Abstract readReview
In one paragraph

Review in Expert review of anti-infective therapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Global epidemiology ofSexually transmitted infections · 2021
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Development and Laboratory Evaluation of aInternational journal of molecular sciences · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Sexually Transmitted Infections in Adolescents and Young Adults: A Cross Section of Public Health.International journal of environmental research and public health · 2024
    Article
  17. Article
  18. Review
  19. Article
  20. A profile of the binx healthExpert review of molecular diagnostics · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Charlotte GaydosDivision of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Justin Hardick

Funding

LC: HIV Prevention Trials Network - Laboratory Support for the SARS-CoV-2 Seroprevalence Study (CoVPN 5002)UM1AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SUSAN H ESHLEMAN, Mark A Marzinke · 2011 to 2026
$100.2M
TrainingU54EB007958 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI Yukari C Manabe · 2007 to 2026
$34.6M
HIV Prevention Trials Network: Network LaboratoryU01AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI ESHLEMAN, SUSAN H · 2006 to 2010
$16.5M
NIAID NIH HHS U01 AI068613NIAID NIH HHS U-01 AM AI 068613NIAID NIH HHS UM1 AI068613NIBIB NIH HHS U-54 EB 007958NIBIB NIH HHS U54 EB007958
6 · The paper itself

Abstract

Accurate and inexpensive point-of-care (POC) tests are urgently needed to control sexually transmitted infection epidemics, so that patients can receive immediate diagnoses and treatment. Current POC assays for Chlamydia trachomatis and Neisseria gonorrhoeae perform inadequately and require better assays. Diagnostics for Trichomonas vaginalis rely on wet preparation, with some notable advances. Serological POC assays for syphilis can impact resource-poor settings, with many assays available, but only one available in the U.S. HIV POC diagnostics demonstrate the best performance, with excellent assays available. There is a rapid assay for HSV lesion detection; but no POC serological assays are available. Despite the inadequacy of POC assays for treatable bacterial infections, application of technological advances offers the promise of advancing POC diagnostics for all sexually transmitted infections.

Indexed as

Point-of-Care SystemsChlamydia InfectionsChlamydia trachomatisFemaleGonorrheaHIVHIV InfectionsHumansMaleNeisseria gonorrhoeaeSexually Transmitted DiseasesSyphilisTreponema pallidumTrichomonas vaginalisTrichomonas VaginitisChlamydia trachomatisHIVHSV-2Neisseria gonorrhoeaePCRpoint-of-care diagnosticsresource-limited settingsserologysyphilisTrichomonas vaginalis

Identifiers

PMID24484215
PMCPMC4065592

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.