Evidence map›Paper›PMID 24483704›Full record

ArticlePhysical review letters2013

Escape of DNA from a weakly biased thin nanopore: experimental evidence for a universal diffusive behavior.

David P Hoogerheide, Fernando Albertorio, Jene A Golovchenko

Abstract read
In one paragraph

Article in Physical review letters, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Counter-Intuitive Features of Particle Dynamics in Nanopores.International journal of molecular sciences · 2023
    Review
  2. Article
  3. Article
  4. Article
  5. PPDiffuse: A Quantitative Prediction Tool for Diffusion of Charged Polymers in a Nanopore.Journal of research of the National Institute of Standards and Technology · 2020
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Thermal Motion of DNA in an MspA Pore.Biophysical journal · 2015
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David P HoogerheideDepartment of Physics, Harvard University, Cambridge, Massachusetts 02138, USA.
Fernando AlbertorioDepartment of Physics, Harvard University, Cambridge, Massachusetts 02138, USA.
Jene A GolovchenkoDepartment of Physics, Harvard University, Cambridge, Massachusetts 02138, USA and School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA.

Funding

Electronic Sequencing in NanoporesR01HG003703 · NHGRI · HARVARD UNIVERSITY · PI BRANTON, DANIEL NONE, GOLOVCHENKO, JENE A · 2005 to 2014
$16.1M
NHGRI NIH HHS HG003703NHGRI NIH HHS R01 HG003703
6 · The paper itself

Abstract

We report experimental escape time distributions of double-stranded DNA molecules initially threaded halfway through a thin solid-state nanopore. We find a universal behavior of the escape time distributions consistent with a one-dimensional first passage formulation notwithstanding the geometry of the experiment and the potential role of complex molecule-liquid-pore interactions. Diffusion constants that depend on the molecule length and pore size are determined. Also discussed are the practical implications of long time diffusive molecule trapping in the nanopore.

Indexed as

Models, ChemicalNanoporesDiffusionDNADNA

Identifiers

PMID24483704
PMCPMC4085674

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.