ArticleScience (New York, N.Y.)2014
Effector specialization in a lineage of the Irish potato famine pathogen.
Article in Science (New York, N.Y.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
87 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The front line of defence: a meta-analysis of apoplastic proteases in plant immunity.Journal of experimental botany · 2021Pooled it
- Evolutionary History and Diversification of M35 Metalloproteases in Dothideomycetes: A Phylogenomic Overview and Case Study in Corynespora cassiicola.Current microbiology · 2026Article
- Specific selection on XEG1 and XLP1 genes correlates with host range and adaptability in Phytophthora.Nature communications · 2025Article
- Genome-wide Evidence of Host Specialization in Wild and Farmland Populations of the Fungal Leaf Spot Pathogen, Cercospora beticola.Genome biology and evolution · 2025Article
- NbPIRIN promotes the protease activity of papain-like cysteine protease NbRD21 to inhibit Chinese wheat mosaic virus infection.PLoS pathogens · 2025Article
- Conserved effector families render Phytophthora species vulnerable to recognition by NLR receptors in nonhost plants.Nature communications · 2024Article
- Plant PR1 rescues condensation of the plastid iron-sulfur protein by a fungal effector.Nature plants · 2024Article
- The pathogenicity of Plasmopara viticola: a review of evolutionary dynamics, infection strategies and effector molecules.BMC plant biology · 2024Review
- NIa-Pro of sugarcane mosaic virus targets Corn Cysteine Protease 1 (CCP1) to undermine salicylic acid-mediated defense in maize.PLoS pathogens · 2024Article
- A plant cell death-inducing protein from litchi interacts with Peronophythora litchii pectate lyase and enhances plant resistance.Nature communications · 2024Article
- BASIDIN as a New Protein Effector of the Phytopathogen Causing Witche's Broom Disease in Cocoa.International journal of molecular sciences · 2023Article
- Hybridisation has shaped a recent radiation of grass-feeding aphids.BMC biology · 2023Article
- Convergent evolution of immune receptors underpins distinct elicitin recognition in closely related Solanaceous plants.The Plant cell · 2023Article
- Article
- Fungal Effectoromics: A World in Constant Evolution.International journal of molecular sciences · 2022Review
- Regressive evolution of an effector following a host jump in the Irish potato famine pathogen lineage.PLoS pathogens · 2022Article
- Co-evolved plant and blast fungus ascorbate oxidases orchestrate the redox state of host apoplast to modulate rice immunity.Molecular plant · 2022Article
- Leveraging genomics to understand the broader role of fungal small secreted proteins in niche colonization and nutrition.ISME communications · 2022Review
- Temperature-dependent genetics of thermotolerance between yeast species.Frontiers in ecology and evolution · 2022Article
- Review
27 more citing papers are in PubMed but not listed here.
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Authors and funding
15 authors.
Funding
Abstract
Accelerated gene evolution is a hallmark of pathogen adaptation following a host jump. Here, we describe the biochemical basis of adaptation and specialization of a plant pathogen effector after its colonization of a new host. Orthologous protease inhibitor effectors from the Irish potato famine pathogen, Phytophthora infestans, and its sister species, Phytophthora mirabilis, which is responsible for infection of Mirabilis jalapa, are adapted to protease targets unique to their respective host plants. Amino acid polymorphisms in both the inhibitors and their target proteases underpin this biochemical specialization. Our results link effector specialization to diversification and speciation of this plant pathogen.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.