ArticleMethods in molecular biology (Clifton, N.J.)2014
Generation of closed transverse fractures in small animals.
Article in Methods in molecular biology (Clifton, N.J.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Polytrauma impairs fracture healing accompanied by increased persistence of innate inflammatory stimuli and reduced adaptive response.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Callus γδ T cells and microbe-induced intestinal Th17 cells improve fracture healing in mice.The Journal of clinical investigation · 2023Article
- Prx1 cell subpopulations identified in various tissues with diverse quiescence and activation ability following fracture and BMP2 stimulation.Frontiers in physiology · 2023Article
- Review
- A segmental defect adaptation of the mouse closed femur fracture model for the analysis of severely impaired bone healing.Animal models and experimental medicine · 2020Article
- Characterization of a reproducible model of fracture healing in mice using an open femoral osteotomy.Bone reports · 2020Article
- A methodology for the generation and non-destructive characterisation of transverse fractures in long bones.Bone reports · 2018Article
- Correlation between RUST assessments of fracture healing to structural and biomechanical properties.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2018Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The most common procedure that has been developed for use in rats and mice to model fracture healing is described. The nature of the regenerative processes that may be assessed and the types of research questions that may be addressed with this model are briefly outlined. The detailed surgical protocol to generate closed simple transverse fractures is presented, and general considerations when setting up an experiment using this model are described.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.