ReviewMethods in molecular biology (Clifton, N.J.)2014
Overview of skeletal repair (fracture healing and its assessment).
Review in Methods in molecular biology (Clifton, N.J.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
- Non-steroidal anti-inflammatory drugs and bone healing in animal models-a systematic review and meta-analysis.Systematic reviews · 2021Pooled it
- How the anatomic location affects the surgical outcomes of simple bone cysts in children: a single-center retrospective cohort study.Journal of orthopaedic surgery and research · 2026Article
- Could Trace Elements be Linked to Fracture Healing Acceleration in Traumatic Brain Injury-related Skeletal Polytrauma?Biological trace element research · 2026Article
- Biomimetic Dual-Sensing Bone Scaffolds: Characterization and In Vitro Evaluation Under Dynamic Culturing Conditions.Biomimetics (Basel, Switzerland) · 2025Article
- Quantitative evaluation of fracture healing progression in rat femurs with modal damping factor and conventional methods.Frontiers in bioengineering and biotechnology · 2025Article
- Bone adhesive materials: From bench to bedside.Materials today. Bio · 2023Review
- Acute Correction of Femoral Malrotation After Intramedullary Nailing Using an Intraoperative Digital Protractor.Cureus · 2023Article
- AnFrontiers in bioengineering and biotechnology · 2023Article
- A medical ethics review of elective orthopaedic surgery management during the pandemic COVID-19 Era.Annals of medicine and surgery (2012) · 2022Review
- Heterotopic ossification vs. fracture healing: Extracellular vesicle cargo proteins shed new light on bone formation.Bone reports · 2022Article
- Article
- Fracture Healing Research-Shift towards In Vitro Modeling?Biomedicines · 2021Review
- Gut microbial-derived short-chain fatty acids and bone: a potential role in fracture healing.European cells & materials · 2021Review
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- Article
- A naturally derived small molecule NDSM253 inhibits IKK1 to suppress inflammation response and promote bone healing after fracture.American journal of translational research · 2021Article
- Matrix metalloproteinase (MMP)-degradable tissue engineered periosteum coordinates allograft healing via early stage recruitment and support of host neurovasculature.Biomaterials · 2021Article
- YAP and TAZ Promote Periosteal Osteoblast Precursor Expansion and Differentiation for Fracture Repair.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021Article
- Preclinical safety and efficacy of 24R,25-dihydroxyvitamin DJournal of orthopaedic translation · 2020Article
- VEGFA From Early Osteoblast Lineage Cells (Osterix+) Is Required in Mice for Fracture Healing.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The study of postnatal skeletal repair is of immense clinical interest. Optimal repair of skeletal tissue is necessary in all varieties of elective and reparative orthopedic surgical treatments. However, the repair of fractures is unique in this context in that fractures are one of the most common traumas that humans experience and are the end-point manifestation of osteoporosis, the most common chronic disease of aging. In the first part of this introduction the basic biology of fracture healing is presented. The second part discusses the primary methodological approaches that are used to examine repair of skeletal hard tissue and specific considerations for choosing among and implementing these approaches.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.