ArticleEvolution, medicine, and public health2013
Depressive symptoms are not associated with inflammation in younger and older adults in the Philippines.
Article in Evolution, medicine, and public health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Inflammation and depression in young people: a systematic review and proposed inflammatory pathways.Molecular psychiatry · 2022Pooled it
- Intimate partner violence, depression, and chronic low-grade inflammation among middle-aged women in Cebu, Philippines.American journal of human biology : the official journal of the Human Biology Council · 2024Article
- Inflammation and immune system pathways as biological signatures of adolescent depression-the IDEA-RiSCo study.Translational psychiatry · 2024Article
- Socioeconomic status is negatively associated with immunosenescence but positively associated with inflammation among middle-aged women in Cebu, Philippines.Brain, behavior, and immunity · 2024Article
- Three common assumptions about inflammation, aging, and health that are probably wrong.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Traumatic events and mental health: The amplifying effects of pre-trauma systemic inflammation.Brain, behavior, and immunity · 2021Article
- Posttraumatic Stress Disorder: Does the Gut Microbiome Hold the Key?Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2016Review
- Depression as sickness behavior? A test of the host defense hypothesis in a high pathogen population.Brain, behavior, and immunity · 2015Article
- Links among inflammation, sexual activity and ovulation: Evolutionary trade-offs and clinical implications.Evolution, medicine, and public health · 2015Article
- Microbial 'old friends', immunoregulation and socioeconomic status.Clinical and experimental immunology · 2014Review
- Microbial 'Old Friends', immunoregulation and stress resilience.Evolution, medicine, and public health · 2013Article
- Childhood microbial experience, immunoregulation, inflammation and adult susceptibility to psychosocial stressors and depression in rich and poor countries.Evolution, medicine, and public health · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Depression is positively associated with chronic inflammation in industrialized settings with low burdens of infectious disease, but the pattern of association in environments with higher levels of microbial exposure is not known. We measured C-reactive protein (CRP) and interleukin 6 (IL6) in community-based samples of young adults (20-22 years) and older women (35-69 years) in the Philippines. Concentrations of CRP and IL6 were low, and bivariate and multivariate regression analyses indicated no associations between depressive symptoms and inflammation in either sample. Results are interpreted in light of prior research indicating that higher levels of microbial exposure in infancy have lasting effects on the regulation of inflammation, and may prevent the emergence of a relationship between depression and inflammation in adulthood.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.