ArticleNutrients2014
Effect of fructooligosaccharides fraction from Psacalium decompositum on inflammation and dyslipidemia in rats with fructose-induced obesity.
Article in Nutrients, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 55 citations in OpenAlex.
- Combined Short-Chain Fatty Acids Induce an Anti-Inflammatory and Anti-Chemotactic Secretory Profile from 3T3-L1 Adipocytes in Normoxic and Hypoxic Environmental Conditions.International journal of molecular sciences · 2026Article
- Production and functional applications of fructooligosaccharides and their core bioactive components.World journal of microbiology & biotechnology · 2026Review
- Severity of Hypoxia-Induced Effects on 3T3-L1 Adipocyte Secretory Function Is Attenuated Dose-Dependently by Individual Short-Chain Fatty Acids.Nutrients · 2026Article
- Fructooligosaccharide ameliorates inflammation-induced chronic pain via deactivation of LPS/TLR-4/NF-κB p65/TNF-α/IL-6 pathway in estrogen-deficient rats.Inflammopharmacology · 2026Article
- Effect of a fructooligosaccharides fraction fromBioscience of microbiota, food and health · 2026Article
- Updated Insights into Probiotic Interventions for Metabolic Syndrome: Mechanisms and Evidence.Probiotics and antimicrobial proteins · 2026Review
- Dose-Dependent Effects of Short-Chain Fatty Acids on 3T3-L1 Adipocyte Adipokine Secretion and Metabolic Function.Nutrients · 2025Article
- Accelerated Molecular Transportation in the Brain Extracellular Space with 755-nm Light Attenuates Post-Stroke Cognitive Impairment in Rats.Cyborg and bionic systems (Washington, D.C.) · 2025Article
- Unlocking Cardioprotective Potential of Gut Microbiome: Exploring Therapeutic Strategies.Journal of microbiology and biotechnology · 2024Review
- Antihypertensive, antidyslipidemic, and renoprotective effects ofIranian journal of basic medical sciences · 2023Article
- Review
- Contributions from Mexican Flora for the Treatment of Diabetes Mellitus: Molecules ofMolecules (Basel, Switzerland) · 2021Review
- Molecules Isolated from Mexican Hypoglycemic Plants: A Review.Molecules (Basel, Switzerland) · 2020Review
- Chemoinformatic Analysis of Selected Cacalolides fromMolecules (Basel, Switzerland) · 2018Article
- Effects of ingredients of Korean brown rice cookies on attenuation of cholesterol level and oxidative stress in high-fat diet-fed mice.Nutrition research and practice · 2017Article
- Effect of High Fructose Corn Syrup (HFCS) Intake on the Female Reproductive Organs and Lipid Accumulation in Adult Rats.Development & reproduction · 2017Article
- Article
- Gut Function-Enhancing Properties and Metabolic Effects of Dietary Indigestible Sugars in Rodents and Rabbits.Nutrients · 2015Review
- Immuno-modulator metallo-Peptide reduces inflammatory state in obese zucker fa/fa rats.International journal of biomedical science : IJBS · 2014Article
- Effect ofIranian journal of pharmaceutical research : IJPRArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Psacalium decompositum, commonly known as "Matarique," is a medicinal plant used in Mexico for diabetes mellitus empirical therapy. Previous studies have shown that the fructooligosaccharides (FOS) present in the roots of this plant exhibit a notable hypoglycemic effect in animal models; this effect might be associated with the attenuation of the inflammatory process and other metabolic disorders. In this study, we examined the effects of FOS fraction administration in a fructose-fed rat model for obesity. Phytochemical chromatographic studies (high performance thin layer chromatography and nuclear magnetic resonance) were performed to verify isolation of FOS. 24 male Wistar rats were maintained for 12 weeks on a diet of 20% HFCS in drinking water and chow. Glucose, cholesterol, triglycerides and liver transaminases levels were measured monthly, after administering FOS fraction intragastrically (150 mg/kg/day for 12 weeks), while the levels of inflammatory cytokines were only quantified at the end of the treatments. Rats treated with FOS fraction decreased body weight, cholesterol, triglycerides, and significantly reduced IL-6, IFN-γ, MCP-1, IL-1β and VEGF levels (p < 0.05). These results suggest that P. decompositum has anti-inflammatory and hypolipidemic properties that might be used as an alternative treatment for the control of obesity.
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