ArticleJAMA2014
Returning pleiotropic results from genetic testing to patients and research participants.
Article in JAMA, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Disclosing Pleiotropic Effects During Genetic Risk Assessment for Alzheimer Disease: A Randomized Trial.Annals of internal medicine · 2016Trial
- POIROT: a powerful test for parent-of-origin effects in unrelated samples leveraging multiple phenotypes.Bioinformatics (Oxford, England) · 2023Article
- Psychiatric manifestations of rare variation in medically actionable genes: a PheWAS approach.BMC genomics · 2022Article
- Identification of variants in pleiotropic genes causing "isolated" premature ovarian insufficiency: implications for medical practice.European journal of human genetics : EJHG · 2018Article
- Powerful and robust cross-phenotype association test for case-parent trios.Genetic epidemiology · 2018Article
- Improved ethical guidance for the return of results from psychiatric genomics research.Molecular psychiatry · 2018Article
- Pediatric Issues in Return of Results and Incidental Findings: Weighing Autonomy and Best Interests.Genetic testing and molecular biomarkers · 2017Article
- Which Results to Return: Subjective Judgments in Selecting Medically Actionable Genes.Genetic testing and molecular biomarkers · 2017Article
- Is there evidence that we should screen the general population for Lynch syndrome with genetic testing? A systematic review.Pharmacogenomics and personalized medicine · 2017Review
- Evidence for extensive pleiotropy among pharmacogenes.Pharmacogenomics · 2016Article
- Compare and contrast: a cross-national study across UK, USA and Greek experts regarding return of incidental findings from clinical sequencing.European journal of human genetics : EJHG · 2016Article
- Heimler Syndrome Is Caused by Hypomorphic Mutations in the Peroxisome-Biogenesis Genes PEX1 and PEX6.American journal of human genetics · 2015Article
- Ethical signposts for clinical geneticists in secondary variant and incidental finding disclosure discussions.Medicine, health care, and philosophy · 2015Article
- Genomic screening of the general adult population: key concepts for assessing net benefit with systematic evidence reviews.Genetics in medicine : official journal of the American College of Medical Genetics · 2015Review
- Pleiotropy analysis of quantitative traits at gene level by multivariate functional linear models.Genetic epidemiology · 2015Article
- Leveraging Epidemiologic and Clinical Collections for Genomic Studies of Complex Traits.Human heredity · 2015Article
- Genetic information, non-discrimination, and privacy protections in genetic counseling practice.Journal of genetic counseling · 2014Article
- Delivery of a clinical genomics service.Genes · 2014Review
- Biobanks and personalized medicine.Clinical genetics · 2014Review
- Pharmacogenomics: Current State-of-the-Art.Genes · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
PubMed holds no abstract for this paper.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.