ReviewThe Plant cell2014
PIFs: systems integrators in plant development.
Review in The Plant cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 295 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
295 citing papers in PubMed.
- Photoperiod-dependent regulation of secondary growth by auxin flux: how it occurs and how to benefit from it.Biological reviews of the Cambridge Philosophical Society · 2026Review
- Review
- Nucleoporin Nup96 promotes plant photomorphogenesis by facilitating phyB photobody formation and HOS1-mediated PIF5 degradation in Arabidopsis.Plant communications · 2026Article
- Light at the heart of time: How photoreceptors entrain the circadian clock.Plant communications · 2026Review
- Review
- Phytochrome-interacting factors integrate environmental signals to regulate tomato growth and development.Plant physiology · 2026Article
- Rice adaptation to low-light stress: integrating morpho-physiology, biochemical plasticity, signalling networks and molecular breeding strategies.Plant cell reports · 2026Review
- Biotic Stress Resistance in Sweet Potato: Mechanisms, Perspectives, and Sustainable Production Strategies.Plants (Basel, Switzerland) · 2026Review
- Genome-wide identification of the PIF gene family in broomcorn millet (Panicum miliaceum) highlights PmPIF5 as a candidate regulator of photoperiod responses.BMC plant biology · 2026Article
- Plant movements: navigating the light environment.Plant physiology · 2026Review
- Divergent Regulatory Effects of Jasmonic Acid on Tomato Lycopene Biosynthesis Under Light and Dark Conditions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Single-nucleus transcriptome profiling unveils cell-type-specific ethylene and TOR signaling in tomato.Horticulture research · 2026Article
- Natural variation links seedling hypocotyl growth with water loss in Arabidopsis.The Plant journal : for cell and molecular biology · 2026Article
- An ecology-driven microbial consortium enhances plant growth and immunity while sustaining rhizospheric microbial balance.Plant communications · 2026Article
- Role of CIA2 and CIL in the Regulation of Chloroplast Development During Photomorphogenesis in Arabidopsis.Cells · 2026Article
- DNA Methylation Fine-Tunes Light- and Hormone-Responsive Growth Plasticity inInternational journal of molecular sciences · 2026Article
- Light interacts with mechanical stress to regulate the seed-to-seedling transition.Stress biology · 2025Review
- Transcriptional dynamics and chromatin accessibility in the regulation of shade-responsive genes in Arabidopsis.Genome biology · 2025Article
- Involvement of Phytochrome-Interacting Factors in High-Irradiance Adaptation.International journal of molecular sciences · 2025Article
- Transcriptome Reveals Growth Responses ofBiology · 2025Article
235 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phytochrome-interacting factors (PIFs) are members of the Arabidopsis thaliana basic helix-loop-helix family of transcriptional regulators that interact specifically with the active Pfr conformer of phytochrome (phy) photoreceptors. PIFs are central regulators of photomorphogenic development that act to promote stem growth, and this activity is reversed upon interaction with phy in response to light. Recently, significant progress has been made in defining the transcriptional networks directly regulated by PIFs, as well as the convergence of other signaling pathways on the PIFs to modulate growth. Here, we summarize and highlight these findings in the context of PIFs acting as integrators of light and other signals. We discuss progress in our understanding of the transcriptional and posttranslational regulation of PIFs that illustrates the integration of light with hormonal pathways and the circadian clock, and we review seedling hypocotyl growth as a paradigm of PIFs acting at the interface of these signals. Based on these advances, PIFs are emerging as required factors for growth, acting as central components of a regulatory node that integrates multiple internal and external signals to optimize plant development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.