Evidence map›Paper›PMID 24479797›Full record

ReviewCurrent pharmaceutical design2014

Interrelationships of circulating tumor cells with metastasis and thrombosis: role of microRNAs.

Junli Xue, Victoria K Xie, Peipei Wang, Jiujie Cui, Yong Gao, Zhimin Lu

Abstract readReview
In one paragraph

Review in Current pharmaceutical design, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Cardiovascular disease and survival in non-small cell lung cancer: a multicenter prospective assessment.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2019
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Junli Xue
Victoria K Xie
Peipei Wang
Jiujie Cui
Yong Gao
Zhimin LuDepartment of Neuro- Oncology, Unit 1002, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA, 77030. zhiminlu@mdanderson.org.
Tongji University · CNThe University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
The Role of b-catenin in EGFR-Related Tumor DevelopmentR01CA109035 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LU, ZHIMIN · 2005 to 2016
$2.7M
The Mechanisms of PKM2-Regulated Gene Expression in Tumor Development.R01CA169603 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LU, ZHIMIN · 2013 to 2017
$1.7M
Deciphering the role of Cdc25A in cancer metabolism.R01NS089754 · NINDS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LU, ZHIMIN · 2015 to 2017
$1.1M
NCI NIH HHS 1R0CA169603NCI NIH HHS 2R01CA109035NCI NIH HHS CA16672NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA109035NCI NIH HHS R01 CA169603NINDS NIH HHS R01 NS089754
6 · The paper itself

Abstract

Metastasis and thrombosis are serious threats to cancer patients and generally associated with poor prognosis. The elusive mechanisms underlying the pathogenesis of metastasis and thrombosis have been subjects of extensive investigations. The presence of circulating tumor cells (CTCs) is closely related to tumor metastasis, and these cells play an important role in thrombosis in cancer patients. In this review, we describe the latest findings on the role of CTCs in tumor metastasis and cancer-related thrombosis and the regulatory role of microRNAs in CTCs and thrombosis. Additionally, we discuss anticoagulant-based strategies for the prevention of thrombosis and reduction of cancer metastasis and the potential to translate current knowledge on these strategies to the treatment of cancer.

Indexed as

ThrombosisAnimalsHumansMicroRNAsNeoplasmsNeoplastic Cells, CirculatingPrognosisMicroRNAs

Identifiers

PMID24479797
PMCPMC4448963
OpenAlexW2139979927

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.