ArticleJournal of family medicine and primary care2013
Polypharmacy and potentially inappropriate medication use as the precipitating factor in readmissions to the hospital.
Article in Journal of family medicine and primary care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed, 105 citations in OpenAlex.
- Inappropriate antibiotic utilization in hospitalized patients in Ethiopia: A systematic review and meta-analysis.Exploratory research in clinical and social pharmacy · 2026Review
- Article
- Polypharmacy and potentially-inappropriate medications are prevalent in the elderly cancer patients receiving systemic cancer therapy and they co-relate with adverse outcomes.BMC geriatrics · 2023Article
- An Ontology-Based Approach to Improving Medication Appropriateness in Older Patients: Algorithm Development and Validation Study.JMIR medical informatics · 2023Article
- Social engagement and allostatic load mediate between adverse childhood experiences and multimorbidity in mid to late adulthood: the Canadian Longitudinal Study on Aging.Psychological medicine · 2023Article
- Development of a project for interprofessional collaboration between medical and pharmacy students to improve medication safety in polypharmacy (PILLE).GMS journal for medical education · 2023Article
- Clinical and nutritional predictors of hospital readmission within 30 days.European journal of clinical nutrition · 2022Article
- Evaluation of multiple drug use in patients with type 2 diabetes mellitus.Diabetology international · 2021Article
- Comparison of Multidrug Use in the General Population and among Persons with Diabetes in Denmark for Drugs Having Pharmacogenomics (PGx) Based Dosing Guidelines.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Malnutrition and depression as predictors for 30-day unplanned readmission in older patient: a prospective cohort study to develop 7-point scoring system.BMC geriatrics · 2021Article
- Risk factors for hospital readmission in older adults within 30 days of discharge - a comparative retrospective study.BMC geriatrics · 2020Article
- Drug Use among Nursing Home Residents in Denmark for Drugs Having Pharmacogenomics Based (PGx) Dosing Guidelines: Potential for Preemptive PGx Testing.Journal of personalized medicine · 2020Article
- Pacific meets west in addressing palliative care for Pacific populations in Aotearoa/New Zealand: a qualitative study.BMC palliative care · 2020Article
- Socioeconomic and Demographic Characteristics of US Adults Who Purchase Prescription Drugs From Other Countries.JAMA network open · 2020Article
- Improving prescribing for older patients - 'Yes S-I-R-E!'Singapore medical journal · 2019Observational
- Clinical Conundrums in the Management of Diabetic Ketoacidosis in the Elderly.Journal of translational internal medicine · 2019Article
- Variation of the prevalence of pediatric polypharmacy: A scoping review.Pharmacoepidemiology and drug safety · 2019Article
- Prevalence and risk factors of drug-related hospitalizations in multimorbid patients admitted to an internal medicine ward.PloS one · 2019Observational
- Influence of Education Level of Older Patients on Polypharmacy, Potentially Inappropriate Medications Listed in Beer's Criteria, and Unplanned Hospitalization: A Cross-Sectional Study in Lahore, Pakistan.Medicina (Kaunas, Lithuania) · 2018Article
- Potentially inappropriate medications in community-dwelling older adults undertaken as a comprehensive geriatric risk assessment.European journal of clinical pharmacology · 2018Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimReadmission to the hospital within 30 days of discharge from the hospital is a common occurrence. Congestive heart failure is the most common cause of readmissions in the hospital. We hypothesized that irrespective of the admission diagnosis polypharmacy and potentially inappropriate use of medications (PIM) leads to readmissions within 30 days of discharge from the hospital. MATERIALS AND
methodsA retrospective study was carried out by reviewing the hospital records of 414 patients who were readmitted to the hospital within 30 days of discharge from the hospital between January 2008 and December 2009. The data was stratified to see which patients were on polypharmacy and/or on PIM. Polypharmacy was defined as use of more than 5 medications. PIM was defined as per the modified Beers criteria. Day 0 was defined as the day of discharge and day1 was defined as the day-after Admission to the hospital. Statistical analysis was carried out using a two-way analysis of variance (ANOVA) on the data to see if polypharmacy and/or PIM was related to readmission within 30 days of discharge irrespective of admission diagnosis.
resultsPolypharmacy was related to hospital readmission at day 1 and day 0, however inappropriate drug use was found to be not related at any day. Polypharmacy and PIM combined had a positive correlation to readmission only on days 1 and 0 and it was statistically significant. The use of minimal and appropriate use of drugs was statistically significant compared to polypharmacy and PIM use.
conclusionsPolypharmacy and PIM are under recognized cause of readmissions to the hospital.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.