ArticleJournal of clinical microbiology2014
Bacterial lymphadenitis at a major referral hospital in France from 2008 to 2012.
Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- Limitations of Serological Diagnosis of Typical Cat Scratch Disease and Recommendations for the Diagnostic Procedure.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023Review
- Concurrence of cat-scratch disease and paradoxical tuberculosis-IRIS lymphadenopathy: a case report.BMC infectious diseases · 2022Article
- Repertoire of the gut microbiota from stomach to colon using culturomics and next-generation sequencing.BMC microbiology · 2018Article
- Molecular strategy for the diagnosis of infectious lymphadenitis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018Article
- Article
- Bartonella henselae is usually not viable in lymph nodes of patients with cat scratch disease.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Article
- Case Report: Scalp Eschar and Neck Lymphadenopathy Associated with Bacteremia due toThe American journal of tropical medicine and hygiene · 2017Article
- 'New microbes and new infections · 2017Article
- 'New microbes and new infections · 2017Article
- 'New microbes and new infections · 2017Article
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- 'New microbes and new infections · 2017Article
- Candidatus Coxiella massiliensis Infection.Emerging infectious diseases · 2016Article
- Blood-Borne Candidatus Borrelia algerica in a Patient with Prolonged Fever in Oran, Algeria.The American journal of tropical medicine and hygiene · 2015Article
- Positron emission tomography in the diagnosis of Whipple's endocarditis: a case report.BMC research notes · 2015Article
- Methods for the discovery of emerging pathogens.Microbial pathogenesis · 2014Review
- [Histopathological study of cervical lymphadenopathy in Yaounde, Cameroon].The Pan African medical journal · 2014Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lymph node enlargement is a common medical problem, and in a large number of patients, the causes of lymphadenopathy remain undiagnosed. We report a thorough microbiological analysis of 1,688 lymph node biopsy specimens collected in our bartonellosis reference center. We studied lymph node biopsy samples from patients with suspected regional infectious lymph node enlargement from January 2008 to December 2012. To evaluate a useful strategy for the diagnosis of infectious lymphadenitis, specimens were cultured and subjected to molecular assays. Histologic analysis was done when possible. A total of 642 (38%) biopsy specimens were infected with a bacterial agent, and quantitative PCR (qPCR) was significantly better than 16S rRNA gene PCR (rrs) for the detection of Bartonella henselae (P = 0.05), Mycobacterium tuberculosis (P = 0.05), and Mycobacterium avium (P = 0.007). Molecular assays were significantly better than bacterial cultures for the diagnosis of Francisella tularensis (P = 0.017) but were less effective for detecting M. tuberculosis (P = 0.004) and M. avium (P = 0.001). Histologic analysis was done for 412 lymph nodes, and 20% of these were compatible with an infectious lymphadenitis, whereas a neoplasm was found in 29% of these lymph nodes. M. tuberculosis was detected significantly more in female than in male patients (P = 0.01), and patients with cat scratch disease (CSD) were younger than patients with M. tuberculosis, Tropheryma whipplei, and F. tularensis. Negative rrs PCR does not exclude the diagnosis of infectious lymphadenitis. Histologic analysis of lymph node biopsy specimens is critical, as a diagnosis of infectious lymphadenitis does not preclude other concurrent diseases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.