Evidence map›Paper›PMID 24478404›Full record

ArticleJournal of clinical microbiology2014

Comparison of two assays for molecular determination of rifampin resistance in clinical samples from patients with Buruli ulcer disease.

Moritz Jansson, Marcus Beissner, Richard Odame Phillips, Kossi Badziklou, Ebekalisai Piten, Issaka Maman, Fred Stephen Sarfo, Kristina Lydia Huber, Agata Rhomberg, Dominik Symank and 8 more

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Pharmacologic management ofExpert review of clinical pharmacology · 2020
    Review
  3. Article
  4. Article
  5. Article
  6. In Silico Prediction of Antibiotic Resistance inThe American journal of tropical medicine and hygiene · 2017
    Article
  7. Susceptibility Profiles ofInternational journal of microbiology · 2016
    Article
  8. Article
  9. Genotyping Tools forMycobacterial diseases : tuberculosis & leprosy · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Moritz JanssonDepartment of Infectious Diseases and Tropical Medicine (DITM), University Hospital, Ludwig-Maximilians-University, Munich, Germany.
Marcus Beissner
Richard Odame Phillips
Kossi Badziklou
Ebekalisai Piten
Issaka Maman
Fred Stephen Sarfo
Kristina Lydia Huber
Agata Rhomberg
Dominik Symank
Magdalena Wagner
Franz Wiedemann
Jörg Nitschke
Abiba Banla Kere
Karl-Heinz Herbinger
Ohene Adjei
Thomas Löscher
Gisela Bretzel

Funding

Medical Research Council MR/J01477X/1
6 · The paper itself

Abstract

This study evaluates a novel assay for detecting rifampin resistance in clinical Mycobacterium ulcerans isolates. Although highly susceptible for PCR inhibitors in 50% of the samples tested, the assay was 100% M. ulcerans specific and yielded >98% analyzable sequences with a lower limit of detection of 100 to 200 copies of the target sequence.

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsBuruli UlcerHumansMicrobial Sensitivity TestsMolecular Diagnostic TechniquesMycobacterium ulceransRifampinSensitivity and SpecificityAnti-Bacterial AgentsRifampin

Identifiers

PMID24478404
PMCPMC3993512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.