ArticleJournal of neurophysiology2014
Theta phase shift in spike timing and modulation of gamma oscillation: a dynamic code for spatial alternation during fixation in rat hippocampal area CA1.
Article in Journal of neurophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Decoding hidden goal-directed navigational states and their neuronal representations using a novel labyrinth paradigm and probabilistic modeling framework.bioRxiv : the preprint server for biology · 2025Article
- Allothetic and idiothetic spatial cues control the multiplexed theta phase coding of place cells.Nature neuroscience · 2025Article
- Review
- Theta phase precession supports memory formation and retrieval of naturalistic experience in humans.Nature human behaviour · 2024Article
- The Hippocampus in Pigeons Contributes to the Model-Based Valuation and the Relationship between Temporal Context States.Animals : an open access journal from MDPI · 2024Article
- Dopamine D4 Receptor Agonist Drastically Increases Delta Activity in the Thalamic Nucleus Reuniens: Potential Role in Communication between Prefrontal Cortex and Hippocampus.International journal of molecular sciences · 2023Article
- Neural computations underlying contextual processing in humans.Cell reports · 2022Article
- Article
- Spontaneous Spiking Is Governed by Broadband Fluctuations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Article
- The Theta Rhythm of the Hippocampus: From Neuronal and Circuit Mechanisms to Behavior.Frontiers in cellular neuroscience · 2021Article
- Disorganization of Oscillatory Activity in Animal Models of Schizophrenia.Frontiers in neural circuits · 2021Review
- Coordination of hippocampal theta and gamma oscillations relative to spatial active avoidance reflects cognitive outcome after febrile status epilepticus.Behavioral neuroscience · 2020Article
- Hippocampal gamma rhythms during Y-maze navigation in the juvenile rat.Hippocampus · 2020Article
- Article
- Hippocampal Sequences During Exploration: Mechanisms and Functions.Frontiers in cellular neuroscience · 2019Review
- Hippocampal Theta-Gamma Coupling Reflects State-Dependent Information Processing in Decision Making.Cell reports · 2018Article
- Slow gamma rhythms in CA3 are entrained by slow gamma activity in the dentate gyrus.Journal of neurophysiology · 2016Article
- Snapshots of the Brain in Action: Local Circuit Operations through the Lens of γ Oscillations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Rhythms of the hippocampal network.Nature reviews. Neuroscience · 2016Review
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Authors and funding
4 authors.
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Abstract
Although hippocampus is thought to perform various memory-related functions, little is known about the underlying dynamics of neural activity during a preparatory stage before a spatial choice. Here we focus on neural activity that reflects a memory-based code for spatial alternation, independent of current sensory and motor parameters. We recorded multiple single units and local field potentials in the stratum pyramidale of dorsal hippocampal area CA1 while rats performed a delayed spatial-alternation task. This task includes a 1-s fixation in a nose-poke port between selecting alternating reward sites and so provides time-locked enter-and-leave events. At the single-unit level, we concentrated on neurons that were specifically active during the 1-s fixation period, when the rat was ready and waiting for a cue to pursue the task. These neurons showed selective activity as a function of the alternation sequence. We observed a marked shift in the phase timing of the neuronal spikes relative to the theta oscillation, from the theta peak at the beginning of fixation to the theta trough at the end of fixation. The gamma-band local field potential also changed during the fixation period: the high-gamma power (60-90 Hz) decreased and the low-gamma power (30-45 Hz) increased toward the end. These two gamma components were observed at different phases of the ongoing theta oscillation. Taken together, our data suggest a switch in the type of information processing through the fixation period, from externally cued to internally generated.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.