Evidence map›Paper›PMID 24478126›Full record

ArticleClinical rheumatology2014

Two Takayasu arteritis patients successfully treated with rituximab.

E Caltran, G Di Colo, G Ghigliotti, R Capecchi, E Catarsi, I Puxeddu, P Migliorini, A Tavoni

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. A 16-year-old girl with sudden heart failure and nephrotic syndrome associated with Takayasu's arteritis.Clinical research in cardiology : official journal of the German Cardiac Society · 2022
    Article
  6. Novel Therapies in Takayasu Arteritis.Frontiers in medicine · 2021
    Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

E CaltranClinical Immunology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, 56126, Pisa, Italy.
G Di Colo
G Ghigliotti
R Capecchi
E Catarsi
I Puxeddu
P Migliorini
A Tavoni
University of Pisa · ITUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Takayasu arteritis (TA) is a rare form of chronic large vessel vasculitis of unknown origin involving the aorta and its major branches. Recently, the involvement of B lymphocytes in TA has been suggested, and active refractory TA patients were successfully treated with B cell depletion therapy (BCDT). We report two cases of patients with TA successfully treated with anti-CD20 monoclonal antibody (rituximab). The favorable outcome of rituximab treatment in our patients also support the view that BCDT can be a useful option for refractory TA, and its potential should be evaluated in controlled trials.

Indexed as

AdultAntibodies, Monoclonal, Murine-DerivedFemaleHumansImmunologic FactorsRituximabTakayasu ArteritisTreatment OutcomeAntibodies, Monoclonal, Murine-DerivedImmunologic FactorsRituximab

Identifiers

PMID24478126
OpenAlexW2022255744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.