ReviewJournal of clinical laboratory analysis2014
Iron metabolism: from health to disease.
Review in Journal of clinical laboratory analysis, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 101 citations in OpenAlex.
- Genome-Wide Approach of Gene-Nutrient Intake Interaction Study for Essential Hypertension in a Large Korean Cohort (KoGES).Nutrients · 2024Article
- Functional iron deficiency anemia in patients with cancer.Blood research · 2024Review
- Review
- Animal models of kidney iron overload and ferroptosis: a review of the literature.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023Review
- Free Radical and Viral Infection: A Review from the Perspective of Ferroptosis.Veterinary sciences · 2023Review
- Review
- Serum albumin and ferritin levels: a practical indicator of prognosis in acute myeloid leukemia over 50 years of age?American journal of blood research · 2022Article
- Toxicological Aspects of Iron Oxide Nanoparticles.Advances in experimental medicine and biology · 2022Article
- Biomarkers in the clinical management of patients with atrial fibrillation and heart failure.Journal of geriatric cardiology : JGC · 2021Article
- Iron overload during the treatment of acute leukemia: pretransplant transfusion experience.International journal of hematologic oncology · 2021Article
- Article
- Comparative Evaluation of Intestinal Absorption and Functional Value of Iron Dietary Supplements and Drug with Different Delivery Systems.Molecules (Basel, Switzerland) · 2020Article
- GC-MS Chemical Characterization and In Vitro Evaluation of Antioxidant and Toxic Effects UsingMedicina (Kaunas, Lithuania) · 2019Article
- Poultry biogas slurry can partially substitute for mineral fertilizers in hydroponic lettuce production.Environmental science and pollution research international · 2019Article
- Tuning the Anti(myco)bacterial Activity of 3-Hydroxy-4-pyridinone Chelators through Fluorophores.Pharmaceuticals (Basel, Switzerland) · 2018Review
- Iron overload induces G1 phase arrest and autophagy in murine preosteoblast cells.Journal of cellular physiology · 2018Article
- No effects without causes: the Iron Dysregulation and Dormant Microbes hypothesis for chronic, inflammatory diseases.Biological reviews of the Cambridge Philosophical Society · 2018Review
- Crucial role of chelatable iron in silver nanoparticles induced DNA damage and cytotoxicity.Redox biology · 2018Article
- Review
- Prophylactic Iron Supplementation in Pregnancy: A Controversial Issue.Biochemistry insights · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIron is vital for almost all living organisms by participating in a wide range of metabolic processes. However, iron concentration in body tissues must be tightly regulated since excessive iron may lead to microbial infections or cause tissue damage. Disorders of iron metabolism are among the most common human diseases and cover several conditions with varied clinical manifestations.
methodsAn extensive literature review on the basic aspects of iron metabolism was performed, and the most recent findings on this field were highlighted as well.
resultsNew insights on iron metabolism have shed light into its real complexity, and its role in both healthy and pathological states has been recognized. Important discoveries about the iron regulatory machine and imbalances in its regulation have been made, which may lead in a near future to the development of new therapeutic strategies against iron disorders. Besides, the toxicity of free iron and its association with several pathologies has been addressed, although it requires further investigations.
conclusionThis review will provide students in the fields of biochemistry and health sciences a brief and clear overview of iron physiology and toxicity, as well as imbalances in the iron homeostasis and associated pathological conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.