Evidence map›Paper›PMID 24477863›Full record

ArticleClinical cardiology2014

Regional variation across the United States in management and outcomes of ST-elevation myocardial infarction: analysis of the 2003 to 2010 nationwide inpatient sample database.

Dhaval Kolte, Sahil Khera, Wilbert S Aronow, Marjan Mujib, Chandrasekar Palaniswamy, Ali Ahmed, William H Frishman, Gregg C Fonarow

Abstract read
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Article in Clinical cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

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12citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Dhaval KolteDepartment of Medicine, New York Medical College, Valhalla, New York.
Sahil Khera
Wilbert S Aronow
Marjan Mujib
Chandrasekar Palaniswamy
Ali Ahmed
William H Frishman
Gregg C Fonarow

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRegional differences in the treatment and outcomes of patients with ST-elevation myocardial infarction (STEMI) within the United States remain poorly understood. HYPOTHESIS: Treatment choice and outcomes in patients with STEMI differ between regions within the United States.

methodsWe used the 2003 to 2010 Nationwide Inpatient Sample databases to identify all patients age ≥ 40 years hospitalized with STEMI. Patients were divided into 4 groups according to region: Northeast, Midwest, South, and West. Multivariable logistic regression was used to identify differences in treatment choice and outcomes (in-hospital mortality, acute stroke, and cardiogenic shock) among the 4 regions.

resultsOf 1,990,486 patients age ≥ 40 years with STEMI, 350,073 (17.6%) were hospitalized in the Northeast, 483,323 (24.3%) in the Midwest, 784,869 (39.4%) in the South, and 372,222 (18.7%) in the West. Compared with the Northeast, patients in the Midwest, South, and West were less likely to receive medical therapy alone and more likely to receive percutaneous coronary intervention and coronary artery bypass grafting. Risk-adjusted in-hospital mortality was higher in the Midwest (odds ratio [OR]: 1.07, 95% confidence interval [CI]: 1.05-1.09, P <0.001), South (OR: 1.03, 95% CI: 1.01-1.05, P = 0.001), and West (OR: 1.06, 95% CI: 1.04-1.08, P <0.001), as compared with the Northeast. When adjusted further for regional variation in treatment selection, risk-adjusted in-hospital mortality was even higher in the Midwest, West, and South.

conclusionsDespite higher reperfusion and revascularization rates, STEMI patients in the Midwest, West, and South have paradoxically higher risk-adjusted in-hospital mortality as compared with patients in the Northeast.

Indexed as

AgedFemaleHospital MortalityHumansInpatientsLogistic ModelsMaleMiddle AgedMyocardial InfarctionRisk FactorsShock, CardiogenicStrokeTreatment OutcomeUnited States

Identifiers

PMID24477863
PMCPMC6649537

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.