Evidence map›Paper›PMID 24477392›Full record

Trial reportLasers in medical science2014

Low-level laser therapy with a wrist splint to treat carpal tunnel syndrome: a double-blinded randomized controlled trial.

Yupadee Fusakul, Thanyaporn Aranyavalai, Phongphitch Saensri, Satit Thiengwittayaporn

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Lasers in medical science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03580265 (Efficacy of Laser Acupuncture for Carpal Tunnel Syndrome), which is not on this map. Cited by 25 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 9 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03580265 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Efficacy of Laser Acupuncture for Carpal Tunnel Syndrome

TypeinterventionalSponsorTri-Service General Hospital (TSGH)Ran2019 to 2019Enrolled40ConditionsCarpal Tunnel SyndromeArmslaser phototherapy device with low level laser
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 9 syntheses or guidelines pooled it, 61 citations in OpenAlex.

  1. Pooled it
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  7. Low-level laser therapy for carpal tunnel syndrome.The Cochrane database of systematic reviews · 2017
    Pooled it
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  10. Trial
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  12. Article
  13. Review
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  15. Article
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  18. Efficacy of low-level laser therapy in nerve injury repair-a new era in therapeutic agents and regenerative treatments.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yupadee FusakulDepartment of Physical Medicine and Rehabilitation, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Thanyaporn Aranyavalai
Phongphitch Saensri
Satit Thiengwittayaporn
Navamindradhiraj University · THVajira Hospital · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficacy of low-level laser therapy (LLLT) was evaluated in a total of 66 patients with mild to moderate carpal tunnel syndrome (CTS) with a double-blinded randomized controlled study. The patients were randomly assigned into two groups. Group I received 15 sessions of a gallium-aluminum-arsenide laser treatment at a dosage of 18 J per session over the carpal tunnel area with neutral wrist splint. Group II received placebo laser therapy with neutral wrist splint. The patients were evaluated with the following parameters: (1) clinical parameters which consisted of visual analog scale, symptom severity scale, functional status scale, and pinch strength and grip strength before the treatment and at 5- and 12-week follow-ups and (2) electroneurophysiological parameters from nerve conduction study which were evaluated before the treatment and at 12-week follow-up. Fifty nine patients (112 hands: unilateral CTS = 6 hands and bilateral CTS = 106 hands) completed the study. Both groups I and II had n = 56 hands. Improvements were significantly more pronounced in the LLLT-treated group than the placebo group especially for grip strength at 5- and 12-week follow-ups. At 12-week follow-up, distal motor latency of the median nerve was significantly improved in the LLLT group than the placebo group (p < 0.05). LLLT therapy, as an alternative for a conservative treatment, is effective for treating mild to moderate CTS patients. It can improve hand grip strength and electroneurophysiological parameter with a carry-over effect up to 3 months after treatment for grip strength of the affected hands.

Indexed as

Low-Level Light TherapySplintsCarpal Tunnel SyndromeDemographyDouble-Blind MethodFemaleHumansMaleMiddle AgedWrist

Identifiers

PMID24477392
OpenAlexW2075304112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.