ArticleThe international journal of cardiovascular imaging2014
Three-dimensional speckle tracking echocardiography for the preclinical diagnosis of hypertrophic cardiomyopathy.
Article in The international journal of cardiovascular imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis of the normal reference value of the longitudinal left atrial strain by three dimensional speckle tracking echocardiography.Scientific reports · 2022Pooled it
- Atrial remodelling and dysfunction in hypertrophic cardiomyopathy: prognostic role and therapeutic target.Frontiers in cardiovascular medicine · 2025Review
- Multimodal ultrasound assessment of myocardial perfusion and contractile function in patients with hypertrophic cardiomyopathy and their first-degree relatives.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Article
- Three-dimensional echocardiography for the evaluation of hypertrophic cardiomyopathy patients: relation to symptoms and exercise capacity.The international journal of cardiovascular imaging · 2023Article
- Multimodality Imaging in Sarcomeric Hypertrophic Cardiomyopathy: Get It Right…on Time.Life (Basel, Switzerland) · 2023Review
- Causes of altered ventricular mechanics in hypertrophic cardiomyopathy: an in-silico study.Biomedical engineering online · 2021Article
- Echocardiographic tissue imaging evaluation of myocardial characteristics and function in cardiomyopathies.Heart failure reviews · 2021Review
- A review of current trends in three-dimensional analysis of left ventricular myocardial strain.Cardiovascular ultrasound · 2020Review
- Evaluation of hemodynamics in patients with hypertrophic cardiomyopathy by vector flow mapping: Comparison with healthy subjects.Experimental and therapeutic medicine · 2019Article
- Left Ventricular Strain Is Abnormal in Preclinical and Overt Hypertrophic Cardiomyopathy: Cardiac MR Feature Tracking.Radiology · 2019Observational
- Heterogeneity of longitudinal and circumferential contraction in relation to late gadolinium enhancement in hypertrophic cardiomyopathy patients with preserved left ventricular ejection fraction.Japanese journal of radiology · 2018Article
- Complementary Role of Echocardiography and Cardiac Magnetic Resonance in Hypertrophic Cardiomyopathy.Current cardiology reports · 2017Review
- Strain Imaging Echocardiography: What Imaging Cardiologists Should Know.Current cardiology reviews · 2017Article
- The significance of early screening with echocardiography in eosinophilic granulomatosis with polyangiitis.Journal of medical ultrasonics (2001) · 2016Article
- Echocardiographic assessment of left ventricular systolic function: from ejection fraction to torsion.Heart failure reviews · 2016Review
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The aim is to detect early changes in myocardial mechanics in hypertrophic cardiomyopathy (HCM) mutation carriers, three-dimensional speckle tracking echocardiography (3DSTE) was used for screening of family members in the HCM population. Eighty subjects were divided as: HCM mutation carriers (n = 23), manifest HCM patients (n = 28), and normal controls (n = 29). They prospectively underwent 3DSTE for left atrial (LA) and left ventricle (LV) strain analysis. HCM mutation carriers showed significantly higher LA minimum volume (ml/m(2)) (17 ± 6 vs. 14 ± 4, respectively, P = 0.03) and a significantly lower peak atrial longitudinal strain (PALS) (%), (27 ± 5 vs. 31 ± 7, respectively, P = 0.02) when compared to controls. However, no differences were found in global or regional LV systolic myocardial deformation between both groups. Manifest HCM patients, compared to carriers showed significantly higher LA minimum (27 ± 10 vs. 17 ± 6, respectively, P < 0.001) and maximum volume (42 ± 14 vs. 32 ± 8, respectively, P = 0.007) as well as lower LA ejection fraction (%) (35 ± 8 vs. 47 ± 9, respectively, P < 0.001) and PALS (17 ± 5 vs. 27 ± 5, respectively, P < 0.001). Comparing LV strain, HCM patients showed reduced global longitudinal (-11 ± 4 vs. -16 ± 3, respectively, P < 0.001) and area strain (-35 ± 6 vs. -40 ± 5, respectively, P = 0.005). HCM mutation carriers may be distinguished from healthy subjects using 3DSTE through detection of LA dysfunction that may indicate LV diastolic dysfunction. Further research in a larger study population with gene-specific analysis is warranted for potential clinical usefulness of 3DSTE in family screening for HCM.
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