ArticleSocial psychiatry and psychiatric epidemiology2014
The association of Toxoplasma gondii infection with neurocognitive deficits in a population-based analysis.
Article in Social psychiatry and psychiatric epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genome-wide association study in two populations to determine genetic variants associated with Toxoplasma gondii infection and relationship to schizophrenia risk.Progress in neuro-psychopharmacology & biological psychiatry · 2019Pooled it
- Seroprevalence ofPathogens (Basel, Switzerland) · 2025Article
- Host-parasite interaction in latent cerebral toxoplasmosis: The role of cytokine response in a mouse model.Open veterinary journal · 2025Article
- Association of infection withJournal of epidemiology and community health · 2023Article
- Article
- Misdiagnosis of HIV With Toxoplasmosis Encephalopathy With Progressive Memory Loss as the Initial Symptom: A Case Report.Frontiers in neurology · 2022Article
- Epidemiology, Pathophysiology, Diagnosis, and Management of Cerebral Toxoplasmosis.Clinical microbiology reviews · 2021Review
- Neurological and Neurobehavioral Disorders Associated withJournal of parasitology research · 2021Review
- Review
- Association between Toxoplasma gondii seropositivity and serointensity and brain volume in adults: A cross-sectional study.PloS one · 2021Article
- The association of Toxoplasma gondii IgG and cognitive function scores: NHANES 2013-2014.Parasitology international · 2020Article
- Toxoplasma gondii seropositivity and serointensity and cognitive function in adults.PLoS neglected tropical diseases · 2020Article
- Latent Toxoplasmosis Effects on Rodents and Humans: How Much is Real and How Much is Media Hype?mBio · 2020Review
- Article
- Socioeconomic vulnerability associated to Toxoplasma gondii exposure in southern Brazil.PloS one · 2019Article
- Toxoplasma gondii alters NMDAR signaling and induces signs of Alzheimer's disease in wild-type, C57BL/6 mice.Journal of neuroinflammation · 2018Article
- Lower performance of Toxoplasma-infected, Rh-negative subjects in the weight holding and hand-grip tests.PloS one · 2018Article
- Development of a murine vertical transmission model for Toxoplasma gondii oocyst infection and studies on the efficacy of bumped kinase inhibitor (BKI)-1294 and the naphthoquinone buparvaquone against congenital toxoplasmosis.The Journal of antimicrobial chemotherapy · 2017Article
- Neurophysiological Changes Induced by Chronic Toxoplasma gondii Infection.Pathogens (Basel, Switzerland) · 2017Review
- Relationship between Toxoplasma gondii seropositivity and acoustic startle response in an inner-city population.Brain, behavior, and immunity · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
purposeTo examine the relationship between infection with Toxoplasma gondii (toxo) and cognition.
methodsMultivariate logistic regression was used to test the association of toxo seropositivity with indices of cognitive function among over 4,200 adults in the third National Health and Nutrition Examination Survey.
resultsToxo-seropositive participants were more likely than seronegative participants to score in the worst quartile of the simple reaction time test (OR 1.3, 95 % CI 1.0, 1.6), symbol-digit substitution test (SDST, OR 1.5, 95 % CI 1.2, 1.9) and the serial-digit learning test (trials to criterion) (SDLTNT, OR 1.4, 95 % CI 1.1, 1.8) in models adjusted for age, race/ethnicity, gender and foreign birth. After further adjustment for all cofactors, the association between toxo seropositivity and these outcomes was no longer significant. However, seropositivity was associated with worse scores on the SDST (OR 2.9, 95 % CI 1.8, 4.8) among those in the lowest income category and the SDLTNT (OR 1.5, 95 % CI 1.1, 2.5) among those foreign born.
conclusionsToxo seropositivity may be associated with poor cognitive test scores in certain subgroups; however, causation cannot be established in this cross-sectional study.
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