ReviewToxins2014
The impact of Fusarium mycotoxins on human and animal host susceptibility to infectious diseases.
Review in Toxins, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
127 citing papers in PubMed, 310 citations in OpenAlex.
- Dysbiosis of fungal microbiota in the intestinal mucosa of patients with colorectal adenomas.Scientific reports · 2015Trial
- Distinguishing cytotoxicity-associated and direct immunomodulatory effects of enniatins and beauvericin in human immune and intestinal cells.Mycotoxin research · 2026Article
- Impact of Wheat Crop Management on Co-occurrence of Group B Trichothecenes: Crop Practices Influencing DON and Derivatives in Wheat.Journal of agricultural and food chemistry · 2026Article
- Lack of significant impact of deoxynivalenol (DON) on both swine dendritic cell activities and systemic infection caused by a virulent Streptococcus suis serotype 2 strain.Veterinary research · 2026Article
- Synergistic bentonite andVeterinary world · 2026Article
- The Multifaceted Menace ofBiology · 2026Review
- Article
- Can antioxidants' supplementation modulate the impact of dietary deoxynivalenol and zearalenone co-contamination on the systemic and mucosal immune response of weaned pigs?Journal of animal science · 2026Article
- AMP-activated protein kinase-Caspase 6 axis regulation alleviates the combined apoptotic damage caused by deoxynivalenol and fumonisin B1 in mammary glands.NPJ science of food · 2025Article
- Integrative human intervention study for mycotoxin biomarker discovery and toxicokinetic characterization.Scientific reports · 2025Article
- Mycotoxins and the Intestinal Epithelium: From Barrier Injury to Stem Cell Dysfunction.Toxins · 2025Review
- Article
- Effects of a Phytogenic Mycotoxin Detoxifier on Oxidative Status, Health, and Performance in Dairy Sheep.Toxins · 2025Article
- An Attempted Correlation Between the Fecal Microbial Community of Chinese Forest Musk Deer (Animals : an open access journal from MDPI · 2025Article
- Morphological, Physiological, Biochemical, and Molecular Characterization of Fungal Species Associated with Papaya Rot in Cameroon.Journal of fungi (Basel, Switzerland) · 2025Article
- Article
- Aflatoxins and fumonisins co-contamination effects on laying hens and use of mycotoxin detoxifiers as a mitigation strategy.Mycotoxin research · 2025Article
- Fusarium Genome Sequencing and Assembly.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Article
- Awareness of Poultry Farmers of Interconnected Health Risks: A Cross-Sectional Study on Mycotoxins, Biosecurity, and Salmonellosis in Jimma, Ethiopia.Animals : an open access journal from MDPI · 2024Article
67 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Contamination of food and feed with mycotoxins is a worldwide problem. At present, acute mycotoxicosis caused by high doses is rare in humans and animals. Ingestion of low to moderate amounts of Fusarium mycotoxins is common and generally does not result in obvious intoxication. However, these low amounts may impair intestinal health, immune function and/or pathogen fitness, resulting in altered host pathogen interactions and thus a different outcome of infection. This review summarizes the current state of knowledge about the impact of Fusarium mycotoxin exposure on human and animal host susceptibility to infectious diseases. On the one hand, exposure to deoxynivalenol and other Fusarium mycotoxins generally exacerbates infections with parasites, bacteria and viruses across a wide range of animal host species. Well-known examples include coccidiosis in poultry, salmonellosis in pigs and mice, colibacillosis in pigs, necrotic enteritis in poultry, enteric septicemia of catfish, swine respiratory disease, aspergillosis in poultry and rabbits, reovirus infection in mice and Porcine Reproductive and Respiratory Syndrome Virus infection in pigs. However, on the other hand, T-2 toxin has been shown to markedly decrease the colonization capacity of Salmonella in the pig intestine. Although the impact of the exposure of humans to Fusarium toxins on infectious diseases is less well known, extrapolation from animal models suggests possible exacerbation of, for instance, colibacillosis and salmonellosis in humans, as well.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.