ArticleEvolution; international journal of organic evolution2014
The evolutionary dynamics of sexually antagonistic mutations in pseudoautosomal regions of sex chromosomes.
Article in Evolution; international journal of organic evolution, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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37 citing papers in PubMed.
- Evolutionary dynamics of enlarged neo-sex chromosomes and novel pseudoautosomal regions in Sylvioidea songbirds.Communications biology · 2026Article
- Climate change-driven northward expansion of the mediterranean orchid Ophrys apifera from genetic and ecological perspectives.Scientific reports · 2025Article
- Repeatome Dynamics and Sex Chromosome Differentiation in the XY and XYInternational journal of molecular sciences · 2025Article
- The maintenance of genetic polymorphism underlying sexually antagonistic traits.Evolution letters · 2025Article
- Independent evolution of satellite DNA sequences in homologous sex chromosomes of Neotropical armored catfish (Harttia).Communications biology · 2025Article
- Article
- Satellitome analysis on the pale-breasted thrush Turdus leucomelas (Passeriformes; Turdidae) uncovers the putative co-evolution of sex chromosomes and satellite DNAs.Scientific reports · 2024Article
- Evolution of a plant sex chromosome driven by expanding pericentromeric recombination suppression.Scientific reports · 2024Article
- Heterochiasmy and Sex Chromosome Evolution inGenes · 2023Article
- Recent expansion of the non-recombining sex-linked region on Silene latifolia sex chromosomes.Journal of evolutionary biology · 2022Article
- Evolutionary dynamics of pseudoautosomal region 1 in humans and great apes.Genome biology · 2022Article
- Searching for signatures of sexually antagonistic selection on stickleback sex chromosomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Switching it up: algal insights into sexual transitions.Plant reproduction · 2021Article
- Epistatic interactions between sex chromosomes and autosomes can affect the stability of sex determination systems.Journal of evolutionary biology · 2021Article
- Expanding the classical paradigm: what we have learnt from vertebrates about sex chromosome evolution.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- Sex-biased genes and metabolites explain morphologically sexual dimorphism and reproductive costs in Salix paraplesia catkins.Horticulture research · 2021Article
- Evolutionary dynamics of the human pseudoautosomal regions.PLoS genetics · 2021Article
- Gene-Level, but Not Chromosome-Wide, Divergence between a Very Young House Fly Proto-Y Chromosome and Its Homologous Proto-X Chromosome.Molecular biology and evolution · 2021Article
- Establishment of a new sex-determining allele driven by sexually antagonistic selection.G3 (Bethesda, Md.) · 2021Article
- High-resolution characterization of male ornamentation and re-evaluation of sex linkage in guppies.Proceedings. Biological sciences · 2020Article
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3 authors.
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Abstract
Sex chromosomes can evolve gene contents that differ from the rest of the genome, as well as larger sex differences in gene expression compared with autosomes. This probably occurs because fully sex-linked beneficial mutations substitute at different rates from autosomal ones, especially when fitness effects are sexually antagonistic (SA). The evolutionary properties of genes located in the recombining pseudoautosomal region (PAR) of a sex chromosome have not previously been modeled in detail. Such PAR genes differ from classical sex-linked genes by having two alleles at a locus in both sexes; in contrast to autosomal genes, however, variants can become associated with gender. The evolutionary fates of PAR genes may therefore differ from those of either autosomal or fully sex-linked genes. Here, we model their evolutionary dynamics by deriving expressions for the selective advantages of PAR gene mutations under different conditions. We show that, unless selection is very strong, the probability of invasion of a population by an SA mutation is usually similar to that of an autosomal mutation, unless there is close linkage to the sex-determining region. Most PAR genes should thus evolve similarly to autosomal rather than sex-linked genes, unless recombination is very rare in the PAR.
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