Evidence map›Paper›PMID 24476517›Full record

ArticleArchives of pathology & laboratory medicine2014

Protocol for the examination of specimens from patients with pheochromocytomas and extra-adrenal paragangliomas.

Ozgur Mete, Arthur S Tischler, Ronald de Krijger, Anne Marie McNicol, Graeme Eisenhofer, Karel Pacak, Shereen Ezzat, Sylvia L Asa

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of pathology & laboratory medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. The evolving roles of pathologists in paragangliomas and pheochromocytomas.Virchows Archiv : an international journal of pathology · 2026
    Review
  2. [A Family case of von Hippel-Lindau syndrome].Problemy endokrinologii · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Primary gallbladder paraganglioma: A case report and review of literature.International journal of surgery case reports · 2020
    Article
  13. Review
  14. Review
  15. Article
  16. The diagnosis of bilateral primary renal paragangliomas in a cat.Journal of the South African Veterinary Association · 2017
    Article
  17. Review
  18. Article
  19. Hyperplasia in glands with hormone excess.Endocrine-related cancer · 2016
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Ozgur MeteFrom the Departments of Pathology (Drs Mete and Asa) and Medicine (Dr Ezzat), University Health Network, Toronto, Ontario, Canada; the Department of Pathology, Tufts Medical Center, Boston, Massachusetts (Dr Tischler); the Department of Pathology, Erasmus MC University Medical Center, Rotterdam, The Netherlands (Dr de Krijger); the Department of Molecular and Cellular Pathology, The University of Queensland, University of Queensland Centre for Clinical Research, Royal Brisbane and Women's Hospital, Herston, Brisbane, Australia (Dr McNicol); the Institute of Clinical Chemistry and Laboratory Medicine and Department of Medicine III, University of Dresden, Dresden, Germany (Dr Eisenhofer); and the Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institutes of Health, Bethesda, Maryland (Dr Pacak).
Arthur S Tischler
Ronald de Krijger
Anne Marie McNicol
Graeme Eisenhofer
Karel Pacak
Shereen Ezzat
Sylvia L Asa

Funding

Diagnosis, Pathophysiology And Molecular Biology of Pheochromocytoma and ParagangliomaZIAHD008735 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI PACAK, KAREL · 2009 to 2024
$28.4M
Intramural NIH HHS ZIA HD008735
6 · The paper itself

Abstract

During the last decade there have been revolutionary breakthroughs in understanding the biology of pheochromocytomas and extra-adrenal paragangliomas. Discoveries of new susceptibility genes and genotype-phenotype correlations have led to the realization that appropriate patient care requires a complete integration of clinical, genetic, biochemical, imaging, and pathology findings. Clinical practice has in many cases not kept pace with the rate of discovery, underscoring a need for updated procedures for evaluation of patient specimens and reporting of data. We therefore propose a new synoptic reporting approach for pheochromocytomas and extra-adrenal paragangliomas that will provide clear and uniform information to pathologists and clinicians, in order to advance the diagnosis of these neoplasms and optimize patient care.

Indexed as

Practice Guidelines as TopicAdrenal Gland NeoplasmsBiomarkers, TumorHumansImmunohistochemistryMedical RecordsParaganglioma, Extra-AdrenalPathology, ClinicalPheochromocytomaTumor BurdenBiomarkers, Tumor

Identifiers

PMID24476517
PMCPMC3909881

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.