Evidence map›Paper›PMID 24475421›Full record

ReviewJournal of nephropathology2013

Treatment of renal manifestations of ANCA-associated vasculitis.

Kresimir Galesic, Danica Ljubanovic, Ivica Horvatic

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nephropathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kresimir GalesicDepartment of Nephrology, Dubrava University Hospital, Zagreb Medical School, Zagreb, Croatia.
Danica LjubanovicDepartment of Pathology, Dubrava University Hospital, Zagreb Medical School, Zagreb, Croatia.
Ivica HorvaticDepartment of Nephrology, Dubrava University Hospital, Zagreb Medical School, Zagreb, Croatia.
University Hospital Dubrava · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

contextVasculitis is a clinicopathological entity characterized by inflammation and necrosis of blood vessels. EVIDENCE ACQUISITIONS: Directory of Open Access Journals (DOAJ), Google Scholar, Pubmed (NLM), LISTA (EBSCO) and Web of Science have been searched.

resultsTwo major autoantigens for ANCA are myeloperoxidase (MPO) and proteinase 3 (PR3), which are proteins in the primary granules of neutrophils and in the lysosomes of monocytes. They are expressed in mature neutrophils of patients with ANCA, while absent in healthy subjects.

conclusionsThe kidney is the most commonly affected vital organ in ANCA-associated vasculitis, and patient outcomes are largely determined by the severity of renal disease at diagnosis and by its response to treatment.

Indexed as

ANCA-associated small-vessel vasculitisAntineutrophil cytoplasmatic autoantibodyChapel Hill Consensus Conference classificationCrescentic glomerulonephritisVasculitis

Identifiers

PMID24475421
PMCPMC3886180
OpenAlexW2113495583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.