ArticleJournal of nephropathology2012
Acute kidney injury: A pediatric experience over 10 years at a tertiary care center.
Article in Journal of nephropathology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 57 citations in OpenAlex.
- Etiology, clinical profile and short-term outcome of acute kidney injury in children at a tertiary care pediatric nephrology center in Pakistan.Renal failure · 2017Observational
- Protection of renal tubular cells by antioxidants: current knowledge and new trends.Cell journal · 2015Article
- Kidney tubular cell protection; recent findings.Iranian journal of pediatrics · 2014Article
- Anethum graveolens and hyperlipidemia: A randomized clinical trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2014Article
- Helicobacter pylori and Serum Magnesium Level in Hemodialysis Patients.Jundishapur journal of microbiology · 2014Article
- Comparative evaluation of three different methods for HbA1c measurement with High-performance liquid chromatography in diabetic patients.Advanced biomedical research · 2014Article
- Comment on: A model for prediction of cisplatin induced nephrotoxicity by kidney weight in experimental rats.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013Article
- Suppressive impact of anethum graveolens consumption on biochemical risk factors of atherosclerosis in hypercholesterolemic rabbits.International journal of preventive medicine · 2013Article
- Comment on: preventive effect of Teucrium polium on learning and memory deficits in diabetic rats.Medical science monitor basic research · 2013Article
- Significance of extracapillary proliferation in IgA-nephropathy patients with regard to clinical and histopathological variables.Hippokratia · 2013Article
- Comment on: The Protective Role of Silymarin and Deferoxamine Against Iron Dextran-Induced Renal Iron Deposition in Male Rats.International journal of preventive medicine · 2013Article
- Anti-phospholipase A2 receptor antibody in idiopathic membranous nephropathy: New concepts.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013Article
- Commentary on: Effects of Cinnamon Consumption on Glycemic Status, Lipid Profile and Body Composition in Type 2 Diabetic Patients.International journal of preventive medicine · 2013Article
- Association of proteinuria with various clinical findings and morphologic variables of oxford classification in immunoglobulin a nephropathy patients.International journal of preventive medicine · 2013Article
- Commentary on: effect of vitamin D on insulin resistance and anthropometric parameters in type 2 diabetes; a randomized double-blind clinical trial.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2013Article
- Efficacy of Co-administration of Garlic Extract and Metformin for Prevention of Gentamicin-Renal Toxicity in Wistar Rats: A Biochemical Study.International journal of preventive medicine · 2013Article
- Immunoglobulin A Nephropathy and Malaria falciparum Infection; a Rare Association.Iranian journal of public health · 2013Article
- Association of serum uric acid with proteinuria in type 2 diabetic patients.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2013Article
- World kidney day 2013: acute kidney injury; a public health aware.Iranian journal of public health · 2013Article
- Chronic kidney disease in children: A report from a tertiary care center over 11 years.Journal of nephropathology · 2012Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe etiology of acute kidney injury (AKI) varies in different countries. In addition, the etiology of AKI in hospitalized children is multifactorial. The importance of diagnosing AKI is not only because of short-term high morbidity and mortality rate, but also for its effect on developing chronic kidney disease.
objectiveswe studied retrospectively AKIs of children who were hospitalized over 10 years in a University hospital. MATERIALS AND
methodsA retrospective analysis of the medical recorded data of 180 children less than 18 years treated for AKI in Alzahra Hospital, Isfahan, Iran, were performed during the period of March 2001 to February 2011. For each patient, demographic and anthropometric data, laboratory data, electrocardiographic findings, ultrasound results, etiology of AKI and short-term outcomes were recorded.
resultsThe male to female ratio was 1.57 to 1. Mean age was 5.28 ± 6.3 (SD) years and the median was 1.8 years. The more frequent age group was children less than 2 years. The mortality rate was 22.2% (40 patients). The mortality was not correlated with age (p= 0.74). Renal replacement therapy was recommended for 62 patients (34.4%). Mean of the first and last glomerular filtration rate (GFR) were 18.33± 1.12 ml/min/1.73 m² and 52.53 ± 2.98 ml/min/1.73 m², respectively. The most common urinary sediment finding in approximately 70% of the patients was either renal epithelial cell or renal cell cast. Increased kidney echogenicity was the most common ultrasound finding (48%). Using ANOVA regression analysis, the etiology of disease was the only predictor of mortality (p=0.0001).
conclusionsWe concluded that the mortality is still high in AKI. Furthermore, the poor outcome (defined as low GFR) are higher among patients with low levels of first GFR and higher RIFLE score.
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