ArticleSubstance abuse and rehabilitation2011
Addiction treatment trials: how gender, race/ethnicity, and age relate to ongoing participation and retention in clinical trials.
Article in Substance abuse and rehabilitation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Gender differences in the impact of psychological distress on methamphetamine use disorder outcomes and treatment effect.Addiction (Abingdon, England) · 2026Pooled it
- Can a participant-referred 'study buddy' increase retention of rural people who use drugs in research? A multi-site, randomized trial.Addiction (Abingdon, England) · 2026Trial
- Gender and addiction and other mental disorders comorbidity: sociodemographic, clinical, and treatment differences.Archives of women's mental health · 2023Trial
- Is level of exposure to a 12-step facilitation therapy associated with treatment outcome?Journal of substance abuse treatment · 2014Trial
- Racial/ethnic differences in the rates and correlates of HIV risk behaviors among drug abusers.The American journal on addictionsTrial
- Predictors of Retention in a Clinical Trial of a Fentanyl Overdose Prevention Intervention: Implications for Supporting Participants' Retention in Harm Reduction Research.Substance use & misuse · 2026Article
- Predictors of clinical trial discontinuation in trichotillomania: a secondary analysis of previous clinical trials.BMC psychiatry · 2025Article
- Predictors of urine toxicology and other biologic specimen missingness in randomized trials of substance use disorders.Drug and alcohol dependence · 2024Article
- Racial and ethnic differences in the degree of participation and retention in a decentralized cohort study of COVID-19 immunization in patients with inflammatory bowel diseases.Journal of clinical and translational science · 2024Article
- Article
- Help-Seeking Behaviors Among Older Adults: A Scoping Review.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2022Article
- Article
- A Gender Perspective of Addictive Disorders.Current addiction reports · 2021Review
- Hispanic participants in the National Institute on Drug Abuse's Clinical Trials Network: A scoping review of two decades of research.Addictive behaviors reports · 2020Article
- Research on women with substance use disorders: Reviewing progress and developing a research and implementation roadmap.Drug and alcohol dependence · 2019Review
- Sex and gender differences in substance use disorders.Clinical psychology review · 2018Review
- Age differences in outcomes among patients in the "Stimulant Abuser Groups to Engage in 12-Step" (STAGE-12) intervention.Journal of substance abuse treatment · 2018Article
- Evaluation of a community-based integrated heroin addiction treatment model in Chinese patients.Oncotarget · 2017Article
- Effect of traumatic event reexposure and PTSD on substance use disorder treatment response.Drug and alcohol dependence · 2016Article
- Nonmedical stimulant use among young Asian-Americans, Native Hawaiians/Pacific Islanders, and mixed-race individuals aged 12-34 years in the United States.Journal of psychiatric research · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
introductionHistorically, racial and ethnic minority populations have been underrepresented in clinical research, and the recruitment and retention of women and ethnic minorities in clinical trials has been a significant challenge for investigators. The National Drug Abuse Treatment Clinical Trials Network (CTN) conducts clinical trials in real-life settings and regularly monitors a number of variables critical to clinical trial implementation, including the retention and demographics of participants. PURPOSE: The examination of gender, race/ethnicity, and age group differences with respect to retention characteristics in CTN trials.
methodsReports for 24 completed trials that recruited over 11,000 participants were reviewed, and associations of gender, race/ethnicity, and age group characteristics were examined along with the rate of treatment exposure, the proportion of follow-up assessments obtained, and the availability of primary outcome measure(s).
resultsAnalysis of the CTN data did not indicate statistical differences in retention across gender or race/ethnicity groups; however, retention rates increased for older participants.
conclusionThese results are based on a large sample of patients with substance use disorders recruited from a treatment-seeking population. The findings demonstrate that younger participants are less likely than older adults to be retained in clinical trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.