ArticlePlant physiology2014
Remarkable reproducibility of enzyme activity profiles in tomato fruits grown under contrasting environments provides a roadmap for studies of fruit metabolism.
Article in Plant physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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Who cites it
68 citing papers in PubMed, 138 citations in OpenAlex.
- A sugar flow model predicts cell dynamics, weight, and quality of tomato at varying sink-source ratios and temperatures.Journal of experimental botany · 2026Article
- Esca disease triggers local transcriptomic response and DNA methylation changes in grapevine.Journal of experimental botany · 2026Article
- Exogenous Salicylic Acid Improves Fruit Yield and Quality ofCurrent issues in molecular biology · 2026Article
- Integrated Transcriptome and Metabolome Analysis of Fruit Quality Variation in 'Sweet100' Tomato Across Different Growth Stages.Foods (Basel, Switzerland) · 2026Article
- Dynamic Characterization of Antioxidant-Related, Non-Volatile, and Volatile Metabolite Profiles of Cherry Tomato During Ripening.Antioxidants (Basel, Switzerland) · 2025Article
- Genome-wide meta-QTL approach identifies consensus loci associated with agriculturally important tomato fruit traits.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Modulating the activity of the APC/C regulator SISAMBA improves the sugar and antioxidant content of tomato fruits.Plant biotechnology journal · 2025Article
- Interspecies predictions of growth traits from quantitative transcriptome data acquired during fruit development.Journal of experimental botany · 2025Article
- Short term effects of biochar on soil chemical properties, growth, yield, quality, and shelf life of tomato.Scientific reports · 2025Article
- Integrated analysis of metabolites and enzyme activities reveals the plasticity of central carbon metabolism in grape (Horticulture research · 2025Article
- Chlorine Modulates Photosynthetic Efficiency, Chlorophyll Fluorescence in Tomato Leaves, and Carbohydrate Allocation in Developing Fruits.International journal of molecular sciences · 2025Article
- Grapevine cell response to carbon deficiency requires transcriptome and methylome reprogramming.Horticulture research · 2025Article
- From Division to Death: Metabolomic Analysis ofPlants (Basel, Switzerland) · 2024Article
- Sustained carbon import supports sugar accumulation and anthocyanin biosynthesis during fruit development and ripening in blueberry (Vaccinium ashei).Scientific reports · 2024Article
- Plant Heterotrophic Cultures: No Food, No Growth.Plants (Basel, Switzerland) · 2024Review
- Plant Life with and without Oxygen: A Metabolomics Approach.International journal of molecular sciences · 2023Review
- Multi-omics quantitative data of tomato fruit unveils regulation modes of least variable metabolites.BMC plant biology · 2023Article
- PANTOTHENATE KINASE4, LOSS OF GDU2, and TRANSPOSON PROTEIN1 affect the canalization of tomato fruit metabolism.Plant physiology · 2023Article
- Impaired cell growth under ammonium stress explained by modeling the energy cost of vacuole expansion in tomato leaves.The Plant journal : for cell and molecular biology · 2022Article
- Grape ASR Regulates Glucose Transport, Metabolism and Signaling.International journal of molecular sciences · 2022Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 3 countries.
Funding
Abstract
To assess the influence of the environment on fruit metabolism, tomato (Solanum lycopersicum 'Moneymaker') plants were grown under contrasting conditions (optimal for commercial, water limited, or shaded production) and locations. Samples were harvested at nine stages of development, and 36 enzyme activities of central metabolism were measured as well as protein, starch, and major metabolites, such as hexoses, sucrose, organic acids, and amino acids. The most remarkable result was the high reproducibility of enzyme activities throughout development, irrespective of conditions or location. Hierarchical clustering of enzyme activities also revealed tight relationships between metabolic pathways and phases of development. Thus, cell division was characterized by high activities of fructokinase, glucokinase, pyruvate kinase, and tricarboxylic acid cycle enzymes, indicating ATP production as a priority, whereas cell expansion was characterized by enzymes involved in the lower part of glycolysis, suggesting a metabolic reprogramming to anaplerosis. As expected, enzymes involved in the accumulation of sugars, citrate, and glutamate were strongly increased during ripening. However, a group of enzymes involved in ATP production, which is probably fueled by starch degradation, was also increased. Metabolites levels seemed more sensitive than enzymes to the environment, although such differences tended to decrease at ripening. The integration of enzyme and metabolite data obtained under contrasting growth conditions using principal component analysis suggests that, with the exceptions of alanine amino transferase and glutamate and malate dehydrogenase and malate, there are no links between single enzyme activities and metabolite time courses or levels.
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