Evidence map›Paper›PMID 24474443›Full record

ArticlePhysiological genomics2014

On form and function: does chromatin packing regulate the cell cycle?

David C Corney, Hilary A Coller

Abstract read
In one paragraph

Article in Physiological genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

David C CorneyMolecular, Cell and Developmental Biology, University of California, Los Angeles, California; and Department of Biological Chemistry, David Geffen School of Medicine, Los Angeles, California.
Hilary A Coller
University of California, Los Angeles · US

Funding

Regulation of actively proliferating and quiescent intestinal stem cellsU01DK085527 · NIDDK · STANFORD UNIVERSITY · PI KUO, CALVIN J · 2009 to 2023
$6.9M
Intestinal Stem Cell Consortium Coordinating CenterU01DK085532 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI NILAND, JOYCE CAROL · 2009 to 2018
$6.5M
The Role of MicroRNAs in Cellular QuiescenceR01GM081686 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI COLLER, HILARY A · 2008 to 2012
$1.4M
A Combined Computational and Experimental Approach to Defining Mechanisms of micrR01GM086465 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI COLLER, HILARY A · 2009 to 2012
$1.1M
Role of Tumor and Stromal Cell Metabolism in Stress Adaptation and ProgressionRC1CA147961 · NCI · RUTGERS, THE STATE UNIV OF N.J. · PI COLLER, HILARY A, RABINOWITZ, JOSHUA D · 2009 to 2010
$1.0M
NCI NIH HHS 1RC1 CA147961-01NIDDK NIH HHS U01DK-085527NIDDK NIH HHS U01 DK085532NIGMS NIH HHS 1R01 GM-081686NIGMS NIH HHS 1R01 GM-086465
6 · The paper itself

Abstract

The Systems Biology of Cell State Regulation Section is dedicated to considering how we can define a cellular state and how cells transition between states. One important decision that a cell makes is whether to cycle, that is, replicate DNA and generate daughter cells, or to exit the cell cycle in a reversible manner. The members of the Systems Biology of Cell State Regulation Editorial Board have an interest in the role of epigenetics and the commitment to a dividing or nondividing state. The ability of cells to transition between proliferating and nonproliferating states is essential for the proper formation of tissues. The ability to enter the cell cycle when needed is necessary for complex multicellular processes, such as healing injuries or mounting an immune response. Cells that fail to quiesce properly can contribute to the formation of tumors. In this perspective piece, we focus on research exploring the relationship between epigenetics and the cell cycle.

Indexed as

Epigenesis, GeneticCell CycleCell ProliferationChromatinFibroblastsGene ExpressionHistone-Lysine N-MethyltransferaseHistonesHumansLysineMethylationModels, GeneticRNA InterferenceSignal TransductionChromatinHistone-Lysine N-MethyltransferaseHistonesKMT5C protein, humanLysineepigeneticshistone modificationsquiescence

Identifiers

PMID24474443
PMCPMC3949104
OpenAlexW2316119217

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.