Evidence map›Paper›PMID 24474104›Full record

ReviewAnais brasileiros de dermatologia

Atopic dermatitis and vitamin D: facts and controversies.

Kleyton de Carvalho Mesquita, Ana Carolina de Souza Machado Igreja, Izelda Maria Carvalho Costa

Open access · goldAbstract readReview
In one paragraph

Review in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 66 citations in OpenAlex.

  1. Trial
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  16. Role of micronutrients in skin health and function.Biomolecules & therapeutics · 2015
    Review
  17. Vitamin D and atopic dermatitis in childhood.Journal of immunology research · 2015
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Kleyton de Carvalho MesquitaUniversity of Brasilia, MD, PhD (in course) in Health Sciences - University of Brasilia (UNB) - Dermatologist at the Federal District Health State Department (SES-DF) - Brasilia (DF), Brazil, BrasiliaDF, Brazil.
Ana Carolina de Souza Machado IgrejaBrasilia University Hospital, University of Brasilia, BrasíliaDF, Brazil, MD, Dermatologist - Residency in Dermatology at the Brasilia University Hospital - University of Brasilia (HUB-UNB) - Brasília (DF), Brazil.
Izelda Maria Carvalho CostaSão Paulo Federal University, BrasíliaDF, Brazil, MD, PhD in Dermatology at São Paulo Federal University (UNIFESP) - Adjunct Professor of Dermatology at the University of Brasilia (UNB). Chief of the Pediatric Dermatology Clinic at Brasilia University Hospital - University of Brasilia (HUB/UNB) - Brasília (DF), Brazil.
Universidade de Brasília · BRUnited States Department of State · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with atopic dermatitis have genetically determined risk factors that affect the barrier function of the skin and immune responses that interact with environmental factors. Clinically, this results in an intensely pruriginous and inflamed skin that allows the penetration of irritants and allergens and predisposes patients to colonization and infection by microorganisms. Among the various etiological factors responsible for the increased prevalence of atopic diseases over the past few decades, the role of vitamin D has been emphasized. As the pathogenesis of AD involves a complex interplay of epidermal barrier dysfunction and dysregulated immune response, and vitamin D is involved in both processes, it is reasonable to expect that vitamin D's status could be associated with atopic dermatitis' risk or severity. Such association is suggested by epidemiological and experimental data. In this review, we will discuss the evidence for and against this controversial relationship, emphasizing the possible etiopathogenic mechanisms involved.

Indexed as

Dermatitis, AtopicHumansRisk FactorsSkinSkin Physiological PhenomenaVitamin DVitamin D DeficiencyVitaminsVitamin DVitamins

Identifiers

PMID24474104
PMCPMC3900346
OpenAlexW2090709234

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.